Transformation of Erythrocytes in Rats of Different Ages

Lomako, V. V.; Shylo, Oleksandr

doi:10.1134/s2079057019030093

Cited by 2 publications

(2 citation statements)

References 12 publications

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“…In BM, pro-B (ProB) cells, late pro-B cells (LPB), immature B cells (IB), CD8 + T cells (T2), dendritic cells (DC, Irf8 + ), pro-erythroblasts (ProE), and erythroblasts (Ery) were reduced during aging and effectively replenished by CR (Figure 2A). Combined with the results obtained via fluorescenceactivated cell sorting (FACS) (Figure S3D), these data support the idea that CR repopulates lymphocytes and erythroblasts in aged individuals (Contreras et al, 2018;Lomako and Shylo, 2019).…”

Section: Reconstitution Of the Cellular Ecosystem Of Aging By Crsupporting

confidence: 84%

Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging

Sun

Geng

et al. 2020

Cell

257

217

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Section: Reconstitution Of the Cellular Ecosystem Of Aging By Crsupporting

confidence: 84%

Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging

Sun

Geng

et al. 2020

Cell

257

217

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“…Factors affecting the transport of oxygen by erythrocytes during exercise. As long as the erythrocyte is alive, its physiological functions can «grow old» [59]. It results in higher membrane penetrability and spherical RBC shape [13].…”

mentioning

confidence: 99%

Oxidative stress as a factor in the deterioration of oxygen transfer during exercise

Gunina¹,

Rybina²,

Ataman³

et al. 2021

Fiziol Zh

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Blood oxygen transport regulation by physical activity increase within training dynamics is provided with different mechanisms: from the quantitative and qualitative erythron restructure (including endogenous erythropoietin rise and main erythrocyte index shifts) to change in haemoglobin affinity to oxygen, its heterogeneous structure and blood flow growth as a result of endothelium hyperpolarisation. However, the erythrocyte itself remains a key performer in blood velocity control, due to its structure and functions. This review summarizes the data of modern scientific literature on the characteristics of erythrocytes, which make these cells one of the key links in the oxygen transport system of the blood. The focus on this property of erythrocytes during physical activity is based on the fact that the athlete’s muscles must be supplied with enough oxygen to ensure high performance. Specific training and extra-training factors affecting the content of erythrocytes have been determined. The membrane structure is treated as a significant erythrocyte part in determining its deformation and microvascular blood transport. Enzymes associated with the erythrocyte membrane and affecting cell viability and performance are described. Besides, it is stressed on monitoring erythrocyte indices via modern equipment and assessing lipid peroxidation, which leads to disorders in erythrocyte membrane structure and functions.

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Transformation of Erythrocytes in Rats of Different Ages

Cited by 2 publications

References 12 publications

Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging

Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging

Oxidative stress as a factor in the deterioration of oxygen transfer during exercise

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