Transforming and integrating STI surveillance to enhance global advocacy and investment in STI control

Taylor, Melanie; Wi, Teodora

doi:10.1002/jia2.25361

Cited by 11 publications

(13 citation statements)

References 12 publications

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“…In addition to contributing to adverse health outcomes, STIs interact with the immune system in genital mucosa sites facilitating HIV acquisition and transmission (Wasserheit, 1992;Mayer and Venkatesh, 2011;Mwatelah et al, 2019). Estimates of curable STIs were higher in the younger age groups, particularly in younger females, which is the same group among whom a peak in HIV incidence occurs (Kharsany et al, 2019), thus the importance of enhanced STI surveillance (Taylor and Wi, 2019) and investment in targeted STI control programs for younger populations (Francis et al, 2018;Kharsany et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

Population prevalence of sexually transmitted infections in a high HIV burden district in KwaZulu-Natal, South Africa: Implications for HIV epidemic control

Kharsany

McKinnon

Lewis

et al. 2020

International Journal of Infectious Diseases

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Background: Sexually transmitted infections (STIs) and Human immunodeficiency virus (HIV) share a complex bidirectional relationship, however, population prevalence and the association between the presence of STIs and HIV in a high HIV burden district in KwaZulu-Natal, South Africa is not known. Methods: A total of 9812 participants aged 15-49 years were enrolled in a cross-sectional populationbased household survey. Participants completed a structured questionnaire and provided first-pass urine (males) or self-collected vulvo-vaginal swabs (females) for the detection of STIs.Results: Prevalence of herpes simplex virus type-2 (HSV-2) was 57.8%, syphilis was 1.6%, Neisseria gonorrhoeae was 2.8%, Chlamydia trachomatis was 7.1%, Trichomonas vaginalis was 9.0%, Mycoplasma genitalium was 5.5% and HIV was 36.3%. HIV positive status was associated with an increased probability of having M. genitalium (aPR = 1.49, 95% CI 1.02-2.19) among males and syphilis (aPR = 2.54, 95% CI 1.32-4.86), N. gonorrhoeae (aPR = 2.39, 95% CI 1.62-3.52), T. vaginalis (aPR = 1.70, 95% CI 1.43-2.01) and M. genitalium (aPR = 1.60, 95% CI 1.15-2.22) among females. HIV viral load 400 copies per mL was associated with an increased probability of N. gonorrhoeae (aPR = 1.91, 95% CI 1.36-2.70), C. trachomatis (aPR = 1.52, 95% CI 1.12-2.05) and M. genitalium (aPR = 1.83, 95% CI 1.27-2.63). Conclusions: The high prevalence of STIs and the association between STIs and HIV, and HIV viral load underscores the public health implications of sustained transmission risk of STIs and HIV. These findings highlight the urgent need for expanding STI surveillance and implementing interventions to monitor and reduce the STI burden.

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Section: Discussionmentioning

confidence: 99%

Population prevalence of sexually transmitted infections in a high HIV burden district in KwaZulu-Natal, South Africa: Implications for HIV epidemic control

Kharsany

McKinnon

Lewis

et al. 2020

International Journal of Infectious Diseases

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“…Further studies are needed to address costs and cost-effectiveness of NAAT-based approaches to STI control. STI prevalence surveys can be conducted alongside those of other biobehavioral surveys to improve STI surveillance and burden estimation among general and at risk populations [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…National, regional, and global estimation of STI prevalence and incidence rely on prevalence surveys among general populations. More often STI prevalence surveys are conducted among women as compared to men [ 6 , 7 ]. This analysis provides valuable methods and STI prevalence data for male military populations in these countries which can be used to estimate national and regional STI burden.…”

Section: Introductionmentioning

confidence: 99%

Is it time to use nucleic acid amplification tests for identification of persons with sexually transmitted infections? evidence from seroprevalence and behavioral epidemiology risk surveys in men with chlamydia and gonorrhea

et al. 2020

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“…Some members of the population are more vulnerable to STIs than others. For example, human papillomavirus (HPV), a disease leading to cancer, infects 290 million women at any given time [ 3 , 5 , 6 ]. Furthermore, the Centers for Disease Control and Prevention (CDC-USA) have acknowledged that, as high as these numbers are, STIs frequently go undiagnosed and thus are underreported, even in countries with high economic development.…”

Section: Introductionmentioning

confidence: 99%

Depression as a Function of Social Support in Transgender and Cisgender Individuals with Sexually Transmitted Diseases

Yousuf

Naz

Roberson

et al. 2021

IJERPH

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This study focused on the relationships among social support, self-esteem, and depression in transgender and cisgender individuals suffering from an incurable or curable sexually transmitted disease. Data were collected from 210 participants with an STI using a semi-structured interview along with culturally adapted standardized instruments. Results indicated no differences between transgender and cisgender groups in depression, although there were large differences in social support and self-esteem. Preliminary regression analysis identified only STI type and duration of STI as significant predictors of depression. However, when moderating roles for both social support and self-esteem were tested, each added to the explained variance and, equally importantly, revealed the effects of both gender status and social support on depression. These findings not only demonstrate how the compound stressors of gender minority status and STI type affect depressive symptoms, but also reveal the critical role that social support can play in mitigating depressive symptoms in those with gender minority status. Findings are interpreted within the context of South/Central Asian cultures that have pre- and post-colonial traditions regarding the social role of non-binary individuals.

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Transforming and integrating STI surveillance to enhance global advocacy and investment in STI control

Cited by 11 publications

References 12 publications

Population prevalence of sexually transmitted infections in a high HIV burden district in KwaZulu-Natal, South Africa: Implications for HIV epidemic control

Population prevalence of sexually transmitted infections in a high HIV burden district in KwaZulu-Natal, South Africa: Implications for HIV epidemic control

Is it time to use nucleic acid amplification tests for identification of persons with sexually transmitted infections? evidence from seroprevalence and behavioral epidemiology risk surveys in men with chlamydia and gonorrhea

Depression as a Function of Social Support in Transgender and Cisgender Individuals with Sexually Transmitted Diseases

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