Transfusion Significantly Increases the Risk for Infection After Splenic Injury

Abstract

The choice between splenectomy and splenic repair does not affect the risk for perioperative infection following injury, whereas blood transfusion significantly increases the risk for perioperative infection, respiratory complication, and admission to the intensive care unit.

Allogenic Blood Transfusion in the First 24 Hours after Trauma Is Associated with Increased Systemic Inflammatory Response Syndrome (SIRS) and Death

“…Blood transfusion was the only variable identified that was independently associated with infection, respiratory complications, and admission to the ICU. Patients who received more than two units of blood had a two-fold increase in these complications, as well as a significant increase in ICU admission (p Ͻ 0.0001) [30]. This current study is in agreement with these previous reports.…”

Laparoscopic vs open splenectomy in the management of hematologic diseases

“…This correlation had already been reported in the literature [6]. In contrast to other reports [8,12,14], splenic weight did not correlate either with operative time or with length of postoperative recovery.…”

Cytokine concentration in stored canine erythrocyte concentrates

“…Blood transfusions are an essential part of the treatment for critically ill human and veterinary patients. Although blood cells are usually evaluated for antigenic compatibility prior to delivery, multiple studies have documented an association between transfusion and adverse events in the recipient . In people with major trauma, blood transfusion has been independently associated with increased risk of infection, development of respiratory complications, and admission into the intensive care unit .…”