Transient Global Amnesia Due to a Dominant Hemisphere Tumor

Abstract

Transient global amnesia is generally regarded as a benign syndrome of probable vascular etiology. We describe a man who experienced a single episode of transient global amnesia and subsequently developed a progressive dominant hemispheric syndrome. Neuroradiologic investigations and the patient's subsequent death strongly suggest that his disease was due to a left temporal-parietal mass lesion. Although the syndrome is most often benign, such patients should be examined for mass lesions.

Transient Global Amnesia: Seven Years of Experience with Diffusion-Weighted Imaging in an Emergency Department

“…The presence of a hippocampal lesion allows the condition to be diagnosed with confidence, but in patients without discernible hippocampal lesions, a different etiology leading to the amnestic syndrome cannot be ruled out. It should also be acknowledged that TGA could be determined by the reported brain lesions other than hippocampal high signal intensities [25,26,27,28,29]. Agosti et al [30] suggested that TGA should be classified as ‘primary TGA’ or ‘TGA with structural brain lesions’, but the cited authors reported that both subtypes had comparable clinical features and were clinically indistinguishable.…”

Internal Jugular Vein Valve Incompetence Is Highly Prevalent in Transient Global Amnesia

“…В исследованиях с исполь-зованием диффузионно-взвешенной магнитно-резо-нансной томографии (ДВ-МРТ) были обнаружены незначительные, остро возникшие изменения в меди-альных областях височных долей у небольшого числа пациентов с клиническим диагнозом ТГА [8]. Другие авторы предположили наличие связи ТГА с эпилепсией [9,10] и опухолями головного мозга [11,12].…”

“…8 Other authors have suggested an epileptic etiology 9,10 and association with brain tumors. 11,12 In recent years, the theory of brain venous congestion has been proposed. 5,13 The main brain venous drainage is attained through the sinuses that end in the internal jugular vein (IJV).…”

Transient global amnesia.

“…TGA has been associated with a number of other disorders including mi graine, 4, 7 intracerebral tumor, 5,6 diazepam overdose, 7 cardiac arrhythmia, 8 presumed embolism during coro nary angiography, globin, hematocrit, serum electrolytes, and fasting blood sugar have been normal. Abnormalities, if pres ent, tend to occur in angiographic and encephalographic examinations.…”