“TransIent perivascular inflammation of the carotid artery (TIPIC) syndrome” as a rare case of laterocervical pain: Multimodal diagnosis

Maggialetti, Nicola; Marco, Ilaria De; Sasso, Sara; Farchi, Giuseppe; Ianora, Amato Antonio Stabile; Lucarelli, Nicola Maria; Scardapane, Arnaldo

doi:10.1016/j.radcr.2022.04.021

Cited by 7 publications

(21 citation statements)

References 9 publications

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“…2,4 Restriction on diffusion-weighted imaging and enhancement on post-contrast imaging are also commonly seen. 2,7 Mild luminal stenosis may be seen in a few cases. Histopathologically, Upton et al confirmed non-specific inflammation in the involved vessel wall.…”

Section: Discussionmentioning

confidence: 99%

“…Eccentric involvement at carotid bifurcation is a common pattern. 2,4 Restriction on diffusion-weighted imaging and enhancement on post-contrast imaging are also commonly seen. 2,7 Mild luminal stenosis may be seen in a few cases.…”

Section: Discussionmentioning

confidence: 99%

“…Maggialetti et al 2 proposed four diagnostic criteria of TIPIC syndrome: acute ipsilateral radiating or non-radiating neck pain, perivascular soft tissue infiltration, exclusion of other causes of neck pain, and improvement within 2 weeks with or without anti-inflammatory drugs. Additionally, a minor criterion of intimal soft plaque was also proposed which may be formed secondary to the healing of the inflammation.…”

Section: Discussionmentioning

confidence: 99%

“…4 There may be involvement of common carotid artery, internal carotid artery, or both. 2,4,6 Unilateral involvement is more common than bilateral. Eccentric involvement at carotid bifurcation is a common pattern.…”

Section: Discussionmentioning

confidence: 99%

“…1 Referred pain in the periauricular and periorbital region may also be seen due to stimulation of the sympathetic plexus around the carotid artery. 2,3 Lecler et al 4 have reported an incidence of 2.8% in patients presenting with acute neck pain. International Classification of Headache Disorders (ICHD-2) removed carotidynia from a distinct clinical entity in 2004 and it is now considered a manifestation of various diseases.…”

Section: Introductionmentioning

confidence: 99%

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Radiological presentation of transient perivascular inflammation of carotid artery syndrome in a patient with myelodysplasia

et al. 2023

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Radiological presentation of transient perivascular inflammation of carotid artery syndrome in a patient with myelodysplasia

et al. 2023

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Transient Perivascular Inflammation of the Carotid Artery as a Poorly Recognized Cause of Neck Pain

Greutert,

Schlomer,

Righini

2023

TH Open

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Historically named Idiopathic carotidynia or Fay syndrome,1 Transient Perivascular Inflammation of the Carotid artery (TIPIC) syndrome is a rare condition characterized by inflammation and pain in the carotid artery. The diagnosis requires a specific clinic-radiologic presentation. We describe a 37 year-old female who presented with headaches and left neck pain and was diagnosed with TIPIC syndrome with temporary perivascular infiltration.

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Transient perivascular inflammation of the carotid artery syndrome – A rare differential for anterior neck pain: Series of three cases and review of literature

Kamath,

Kharkhele,

Waghela

et al. 2024

Modern Rheumatology Case Reports

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We report a series of 3 cases of transient perivascular inflammation of the carotid artery (TIPIC) syndrome in an otherwise healthy individual. We would also like to review this rare entity and compare it with other similar cases reported in the literature. Our first case was a young male with right-sided neck pain of 1-week duration with magnetic resonance imaging (MRI) showing right carotid perivascular inflammation which completely resolved after 2 weeks with anti-inflammatory drugs. In the second case, a young male presented with left-sided neck pain and odynophagia of 5 days duration with an MRI showing left carotid perivascular inflammation which completely resolved after 2 weeks with anti-inflammatory drugs. In the third case a young male presented with right-sided neck pain of 1-day duration with an MRI showing right common carotid perivascular inflammation near the bifurcation with complete resolution in pain but with residual wall thickening. We want to highlight the existence of this new entity by reporting these 3 case series with a brief review of the literature. The cause and pathogenesis of this rare entity remain unknown. It has been hypothesized to be autoimmune or viral-mediated inflammation which requires further understanding.

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“TransIent perivascular inflammation of the carotid artery (TIPIC) syndrome” as a rare case of laterocervical pain: Multimodal diagnosis

Cited by 7 publications

References 9 publications

Radiological presentation of transient perivascular inflammation of carotid artery syndrome in a patient with myelodysplasia

Radiological presentation of transient perivascular inflammation of carotid artery syndrome in a patient with myelodysplasia

Transient Perivascular Inflammation of the Carotid Artery as a Poorly Recognized Cause of Neck Pain

Transient perivascular inflammation of the carotid artery syndrome – A rare differential for anterior neck pain: Series of three cases and review of literature

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