Transient Red Blood Cell Aplasia in Association With Viral Hepatitis

Sears, David

doi:10.1001/archinte.1975.00330120063009

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1977

2012

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Cited by 24 publications

(1 citation statement)

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“…Based on the previous reports, a cell- or antibody-mediated immunological process [15,17] or direct infection of hematopoietic progenitor cells by HAV [3,4] might be involved in the pathogenesis of PRCA associated with hepatitis A. Further research is needed to obtain more conclusive information about the pathogenetic mechanisms and related risk factors.…”

Section: Discussionmentioning

confidence: 99%

Corticosteroid Treatment of Pure Red Cell Aplasia in a Patient with Hepatitis A

Yoon

Park²,

Kim³

et al. 2012

Acta Haematol

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Secondary pure red cell aplasia (PRCA), as an extrahepatic manifestation of hepatitis A virus infection, has been reported on rare occasions. We report herein an unusual case of hepatitis A complicated by PRCA. In addition, we reviewed nine cases reported in the English literature. Our case of nonfulminant hepatitis A complicated by PRCA and hemolytic anemia was successfully treated with initial transfusion and corticosteroid therapy for 18 weeks. The patient’s hematologic abnormalities and liver function tests re-normalized completely. We review clinical features and effective therapeutic strategies for this disease entity.

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Section: Discussionmentioning

confidence: 99%