Transient Respiratory Difficulty following Cesarian Delivery

Patel, Daksha M.; Donovan, Edward F.; Keenan, William

doi:10.1159/000241621

Cited by 7 publications

(3 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, others did not support this. 20 TTN was strongly associated with lower GA, whereas the association to birthweight was probably related to lower GA. In Israel in general, and specifically in our population, dating of GA is very accurate, because most pregnant women are closely observed by obstetricians from early weeks of gestation and multiple ultrasonographic evaluations are readily available.…”

Section: Discussionmentioning

confidence: 86%

Cesarean Section, Gestational Age, and Transient Tachypnea of the Newborn: Timing Is the Key

et al. 2005

View full text Add to dashboard Cite

The purpose of this study was to identify risk factors and to characterize infants with transient tachypnea of the newborn (TTN). A total of 67 newborns with TTN, born at gestational age (GA)>or=35 weeks, were studied. Newborns delivered before and after each study case served as controls. Mean GA was lower and cesarean section (CS) rate was higher in the TTN group (38.2+/-2.3 versus 39.5+/-1.4 weeks, p<0.001; 50.7% versus 22.4%, p<0.001). GA<38 weeks was found to be associated with increased risk for TTN in infants delivered by elective CS. TTN was associated with significant morbidities and longer hospital stay (7.2+/-5.6 versus 2.9+/-1.4 days; p<0.001). Delivery by CS and younger GA are risk factors for TTN. Although TTN is a self-limited disease, it is associated with significant morbidities. Scheduling elective CS at GA of not less than 38 weeks may decrease the frequency of TTN.

show abstract

Section: Discussionmentioning

confidence: 86%

Cesarean Section, Gestational Age, and Transient Tachypnea of the Newborn: Timing Is the Key

et al. 2005

View full text Add to dashboard Cite

show abstract

“…18 Transient tachypnea was defined as grunting, retractions, respiratory rate > 60/min for more than 6 hr after birth, without oxygen requirements. 19 Hypoglycemia was defined as a plasma glucose concentration < 30 mg/dl in the first 4 hr of life. 20…”

Section: Infant Managementmentioning

confidence: 99%

Management of the Insulin-Dependent Diabetic During Labor and Delivery

Miodovnik¹,

Mimouni²,

Tsang³

et al. 1987

Amer J Perinatol

View full text Add to dashboard Cite

Infants of insulin-dependent diabetic mothers are at risk for neonatal polycythemia, hyperbilirubinemia, respiratory distress syndrome (RDS), and hypoglycemia. The purpose of this study was to determine whether labor and delivery management of diabetes may influence the rate of these complications. We hypothesized a priori that: infants of diabetic mothers delivered by cesarean section have a lower rate of neonatal polycythemia and hyperbilirubinemia, but a higher rate of RDS, than infants of diabetic mothers delivered by vaginal route, and poor glycemic control during labor increases the rate of neonatal hypoglycemia. We therefore prospectively studied 122 pregnancies in 100 well-controlled insulin-dependent diabetic mothers. Intravenous glucose and/or insulin was infused during labor to maintain capillary glucose concentration between 70 and 100 mg/dl. Fifty-six pregnancies were concluded by primary or elective cesarean section (group 1), 36 by cesarean section following spontaneous or induced labor (group 2), and 30 by spontaneous or induced vaginal delivery (group 3). Hemoglobin A1, birthweight, and gestational age were similar in all three groups. The rate of neonatal polycythemia was significantly lower in the cesarean section subjects, groups 1 and 2, as compared to group 3 (P less than 0.04). The rate of neonatal hyperbilirubinemia was significantly lower in group 1 (P less than 0.05) as compared to groups 2 and 3. The rate of RDS was higher in group 1 (versus groups 2 or 3), but did not reach significance on initial analysis (P = 0.06); however, group 1 was associated with a significant risk for RDS when corrected for the confounding variables of gestational age and neonatal asphyxia as defined by Apgar scores.(ABSTRACT TRUNCATED AT 250 WORDS)

show abstract

“…[6][7][8][9][10][11] TTN results from delayed clearance of fetal lung fluid at birth 12,13 and occurs in isolation or in association with other neonatal respiratory illnesses, such as surfactant deficiency, 14 neonatal pneumonia 14 and persistent pulmonary hypertension of the newborn. 15,16 While TTN is a self-limiting condition, affected infants often undergo evaluation with laboratory testing, chest radiography and close monitoring in a special care nursery (SCN) or neonatal intensive care unit (NICU).…”

Section: Introductionmentioning

confidence: 99%

Inhaled epinephrine for the treatment of transient tachypnea of the newborn

et al. 2008

View full text Add to dashboard Cite

Objective: Infants with transient tachypnea of the newborn (TTN) have relatively low levels of epinephrine, which is known to mediate fetal lung fluid absorption. Providing exogenous epinephrine could be a valuable diagnostic and therapeutic intervention for this common condition. Our primary objective was to determine if inhaled racemic epinephrine is safe for the treatment of TTN. Our secondary objective was to determine its efficacy.Study Design: We conducted a randomized, blinded, placebo-controlled pilot trial. Inhaled racemic epinephrine or placebo was administered to 20 newborns with TTN. Physiologic variables of cardiopulmonary function were measured during and after treatment.Result: No infant in either the treatment or control arm experienced an adverse event, including tachycardia or hypertension. We did not detect a difference between the two groups regarding rate of resolution of tachypnea. Conclusion:We did not observe any adverse effects of inhaled racemic epinephrine when administered for the treatment of TTN. Larger studies are necessary to determine efficacy.

show abstract

Transient Respiratory Difficulty following Cesarian Delivery

Cited by 7 publications

References 12 publications

Cesarean Section, Gestational Age, and Transient Tachypnea of the Newborn: Timing Is the Key

Cesarean Section, Gestational Age, and Transient Tachypnea of the Newborn: Timing Is the Key

Management of the Insulin-Dependent Diabetic During Labor and Delivery

Inhaled epinephrine for the treatment of transient tachypnea of the newborn

Contact Info

Product

Resources

About