Transient tachypnea of the newborn: are there bedside clues for predicting the need of ventilation support?

Kahvecioglu, Dilek; Çakır, Ufuk; Yildiz, Duran; Alan, Serdar; Erdeve, Ömer; Atasay, Begüm; Arsan, Saadet

doi:10.24953/turkjped.2016.04.009

Cited by 12 publications

(12 citation statements)

References 16 publications

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“…Higher Downe'sscores were predictive for further respiratory support in our study newborns with higher Downe's score required CPAP for 48hrs similar to the study done by Kahveciogluetalthat higher Silverman scores were predictivefor further respiratory support [17]. [11].…”

Section: Resultssupporting

confidence: 88%

Incidence, clinicalprofile and outcome of transient tachypnea of newborn

et al. 2017

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Introduction: Respiratory distress is a common problem in neonates necessitating admission. Transient tachypnea of newborn (TTNB) is most common after term cesarean delivery. It is characterized by the early onset of tachypnea with retractions, or expiratory grunting and, occasionally, cyanosis. Distinguishing the disease from respiratory distress syndrome (RDS) andother respiratory disorders may be difficult, and TTNB is frequently a diagnosis of exclusion; the distinctive features of TTNB are rapid recovery of the infant and the absence of radiographic findings for RDS (hypoaeration, diffusereticulogranular pattern, air bronchograms) and other lung disorders. Objective: To study incidence, clinical profile of TTNB and to identify clinical clues that may help inprediction of severity of disease and need for early intervention for better outcome in patients with TTNB. Study design: This is a prospective study conducted at a tertiary care institute in late preterm and term babies admitted in neonatal intensive care unit (NICU) with respiratory distress during the study period. Results: Total admissions during study period were 510 of which 22 Newborns had TTNB. The average gestational age of 36+ 1.2 weeks and birth weight of 2924 + 404 gm. Neonates were included in the study following inclusion criteria. Risk factors identified for TTNB includes caesarean section (most common), male sex, infant of diabetic mother. Outcome can be predicted based, on Downe's score at presentation and time of development of respiratory distress after birth. Conclusion: According to this study all late preterm and term newborn delivered through LSCS are at greater risk for developing TTNB and early development of respiratory distress and higher Downe's score at presentation are associated with longer hospital stay.

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Section: Resultssupporting

confidence: 88%

Incidence, clinicalprofile and outcome of transient tachypnea of newborn

et al. 2017

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“…Univariate analysis demonstrated an association between mortality and levels of serum albumin, total calcium, iCa, phosphate, and acidosis. Multivariate regression analysis identified the following independent risk factors of mortality: hypoalbuminemia (albumin < 25 mg/dL) [18], hypocalcemia (iCa < 1.0 mmol/L), hyperphosphatemia (phosphate > 2.6 mmol/L), and acidosis (pH < 7.3) [19,20] (Table 3).…”

Section: Hypocalcemia As An Independent Predictor Of Mortalitymentioning

confidence: 99%

Prognostic Value of Ionized Calcium Levels in Neonatal Sepsis

2020

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“…Previous studies have developed and reported some scoring systems that could be used in newborns and children with respiratory distress (21). Clues associated with disease prognosis have always been useful as supportive data points for physicians and also when informing patients and/or their relatives of the condition (22).…”

Section: Discussionmentioning

confidence: 99%

Prediction of the Course of Transient Tachypnea of the Newborn by Blood Laboratory Parameters at the Time of Admission

Ekmen

Doğan

2021

Iran J Pediatr

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Background: Transient tachypnea of the newborn (TTN) is a common but mild respiratory problem seen in late preterm and term newborns. However, it may sometimes cause severe morbidity. Objectives: Therefore, biomarkers that can predict TTN severity may aid the clinician in determining the need for intensive care. Our aim was to identify whether blood gases and complete blood count parameters could be utilized to predict the severity of TTN.s Methods: We retrospectively examined the medical records of newborns (> 37 weeks gestation, > 2000 grams) diagnosed with TTN who were hospitalized in the Neonatal Intensive Care Unit (NICU) of Karabuk University Faculty of Medicine, Training and Research Hospital, Karabük/Turkey between June 2019 and June 2020. Patients were grouped according to the length of stay in the NICU. Group 1 included patients that did not require NICU monitoring after 48 hours, and group 2 included patients who continued to require NICU monitoring after 48 hours. Blood gases and complete blood count parameters were compared between the two groups. Results: During the study period, 91 newborns were hospitalized in the NICU due to respiratory distress. Thirty-nine patients who did not meet the inclusion criteria were excluded. Gestational age and birth weight were significantly lower in group 2 (P < 0.05). There were no significant differences between the groups in terms of leukocyte count, hemoglobin level, mean platelet volume (MPV), and platelet count. Partial carbon dioxide pressure (PCO2) was significantly elevated, and base excess (BE) was significantly greater in group 2. Conclusions: We determined a relationship between a prolonged stay in NICU and the levels of PCO2 and BE among patients hospitalized with a diagnosis of TTN. Therefore, PCO2 and BE values may be valuable to determine the prognosis of TTN in the early period. Despite being one of the most common causes of intensive care admission in the newborn population, there is limited data on the diagnosis, treatment, and prognosis of TTN; thus, we believe that our results will shed light on this problem.

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Transient tachypnea of the newborn: are there bedside clues for predicting the need of ventilation support?

Cited by 12 publications

References 16 publications

Incidence, clinicalprofile and outcome of transient tachypnea of newborn

Incidence, clinicalprofile and outcome of transient tachypnea of newborn

Prognostic Value of Ionized Calcium Levels in Neonatal Sepsis

Prediction of the Course of Transient Tachypnea of the Newborn by Blood Laboratory Parameters at the Time of Admission

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