Translation and validation of the EORTC brain cancer module (EORTC QLQ-BN20) for use in Iran

Abstract

BackgroundThe aim of this study was to translate the EORTC quality of life questionnaire for brain cancer, the QLQ-BN20, into Persian, and to evaluate its psychometric properties when used among brain cancer patients in Iran.MethodsA standard backward and forward translation procedure was used to generate the Persian language version of the QLQ-BN20. The QLQ-BN20 was administered together with the QLQ-C30 to 194 patients diagnosed with primary brain cancer. Multitrait scaling and confirmatory factor analysis (CFA) were used to evaluate the hypothesized scale structure of the questionnaire. Internal consistency reliability was estimated with Cronbach’s alpha. The ability of the QLQ-BN20 to distinguish between patient subgroups formed on the basis of performance status and cognitive status was evaluated, as was the responsiveness of the questionnaire to changes in performance status over time.ResultsMultitrait scaling and CFA results confirmed the hypothesized scale structure. The measurement model was consistent across men and women. Internal consistency reliability of the multi-item scales ranged from 0.74 to 0.89. The QLQ-BN20 distinguished clearly between patients with relatively good versus poor performance and cognitive status, and changes in scores over time reflected changes observed in performance status ratings.ConclusionsThese results support the validity and reliability of the QLQ-BN20 for use among Iranian patients diagnosed with primary brain cancer. Future studies should examine the psychometrics of the questionnaire when used in patients with brain metastasis.

Validation of the Korean version of the European Organization for Research and Treatment of Cancer brain cancer module (EORTC QLQ-BN20) in patients with brain tumors

“…These results are similar to those of the previous validation studies of the QLQ-BN20 and QLQ-C30 conducted for patients speaking English [1], Persian [6], and 15 other languages [4]. …”

“…These reliability coefficients are higher than those reported in studies of the English [1] and other language versions [4,6]. Our results suggest that the QLQ-BN20 can be used to assess the HRQOL in patients with other brain tumors as well as in those with brain cancer.…”

“…Most scores of the 2 instruments could clearly distinguish between patient groups according to performance status as shown in earlier studies [4,6,10,11]. The second hypothesis, that the 2 instruments could distinguish patients with glioma from those with meningioma, was partially supported.…”

The reliability and validity of the Iranian version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for patients with Bone Metastases: the EORTC QLQ-BM22

“…The translation procedures were conducted in accordance with the official EORTC Translation Guidelines [20,21]. The aim of the translation project was to produce a Persian/Farsi version of the QLQ-BM22, which is conceptually equivalent to the original English version, as well as clear and easy to understand.…”

Translation, Cultural Adaptation and Validation of the Qualiveen‐30 Questionnaire in Persian for Patients with Spinal Cord Injury and Multiple Sclerosis

“…Therefore, it should be interpreted in conjunction with other fit indices. A RMSEA value less than or equal to .08 is considered acceptable, while values equal or higher than 0.90 for the CFI, NNFI are considered acceptable …”