Purpose: To translate, adapt and validate the Endometriosis Health Pro le-5 (EHP-5) in Croatian population.Methods: This validation study is a part of a prospective, observational study (EHP-5 CRO) with aim of implementation of EHP-5 and to provide better insight in quality of life consideration of women with endometriosis in Croatian clinical practice. A 150 consecutive patients with surgically proven endometriosis were enrolled. The translation to Croatian followed standardized procedure. Cronbach's Alpha was calculated to calculate internal consistency reliability of EHP-5. The test-retest reliability was calculated using intraclass correlation coe cient (ICC). The t-test for independent samples was used to assess known-groups validity.Results: Both EHP-5 core and EHP-5 modular parts of the questionnaire had good internal consistency, assessed by the Cronbach's Alpha coe cient (α=0.793 and α=0.842, respectively). Obtained results indicate very good reliability for core as well as for modular part of EHP-5 questionnaire (ICC=0.896 and 0.936, respectively). The independent t-test showed that women who reported their pain with VAS scale 7 or more had signi cantly higher results (p<0.001) on EHP-5 (M=50.63) compared with women who reported their pain 6 or less (M=26.91). Furthermore, we found statistically signi cant difference between women who are infertile with women who are fertile (p<0.001), whereby infertile women had higher average result on EHP-5 (M=49.55) compared with fertile women (M=34.36).
Conclusion:The Croatian version of the EHP-5 have very good psychometric characteristics and can be used as a reliable tool for assessing patients with endometriosis in everyday clinical practice.