Level of stroke knowledge among stroke patients determine their immediate response during stroke attack. Thus, this study was to determine the level of stroke knowledge among stroke patients at Hospital Raja Perempuan Zainab II, Kelantan, Malaysia. A crosssectional survey was carried out among stroke patients admitted to medical and surgical wards of Hospital Raja Perempuan Zainab II. Stroke patients were selected conveniently and the data was collected within eight months period. The Malay version Stroke Knowledge Test scale with 20 items was used to evaluate knowledge on stroke disease. Overall, there were 178 stroke patients involved in this study. The participants' mean age were 59.07 years old with majority falls between 56 to 65 years old (74.7%). Most of them were female (53.4%), Malays (95.5%) and they had multiple medical morbidities. In terms of stroke knowledge level, 45% answered correctly on 9 items, 35% had misconception on 7 items (35%), while 20% wrongly answered on 4 items. This study highlighted that stroke patients had lack of knowledge towards stroke disease. Therefore, conducting stroke education session in routine prior to hospital discharge is important.