Translocation of Gold Nanorod Through a Solid-State Nanopore

Liu, Quanjun; Yao, Hui; Wang, Lei; Hou, Chuanrong; Zhao, Wenyuan

doi:10.1166/sam.2014.2008

Cited by 3 publications

(4 citation statements)

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“…Nanopores are considered to be the most promising technology for single-molecule detection in a solution with a high throughput, low cost, and free label, which can open novel paths to scientific discovery [1]. Nanopores have been used to detect nanometer scale objects, such as nanoparticles [2][3][4], viruses [5][6][7], DNA sequence [8][9][10][11][12][13][14][15][16][17][18][19], and protein molecules [20][21][22][23][24]. The principle is that a biased voltage is applied across a thin membrane containing a nanometer-sized pore.…”

Section: Introductionmentioning

confidence: 99%

Detection of a single enzyme molecule based on a solid-state nanopore sensor

Tan

Liu

et al. 2016

Nanotechnology

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The nanopore sensor as a high-throughput and low-cost technology can detect a single molecule in a solution. In the present study, relatively large silicon nitride (Si3N4) nanopores with diameters of ∼28 and ∼88 nm were fabricated successfully using a focused Ga ion beam. We have used solid-state nanopores with various sizes to detect the single horseradish peroxidase (HRP) molecule and for the first time analyzed single HRP molecular translocation events. In addition, a real-time monitored single enzyme molecular biochemical reaction and a translocation of the product of enzyme catalysis substrates were investigated by using a Si3N4 nanopore. Our nanopore system showed a high sensitivity in detecting single enzyme molecules and a real-time monitored single enzyme molecular biochemical reaction. This method could also be significant for studying gene expression or enzyme dynamics at the single-molecule level.

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Section: Introductionmentioning

confidence: 99%

Detection of a single enzyme molecule based on a solid-state nanopore sensor

Tan

Liu

et al. 2016

Nanotechnology

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“…[4,[6][7][8][9][10] They are characterized by a low density (e.g., 1.74 g/cm 3 ) and useful mechanical properties, such as tensile strength (e.g., 185 MPa), elongation (e.g., 12.5%), and a Young's modulus (41-45 GPa) close to the Young's modulus of human bone. [11][12][13][14] They also show good biocompatibility with the human body. [12][13][14][15] These properties have encouraged researchers to investigate the possibilities of using magnesium alloys in implantology and other areas of medicine.…”

Section: Introductionmentioning

confidence: 99%

“…[11][12][13][14] They also show good biocompatibility with the human body. [12][13][14][15] These properties have encouraged researchers to investigate the possibilities of using magnesium alloys in implantology and other areas of medicine. [16][17][18][19][20][21] The use of this type of material entails many advantages.…”

Section: Introductionmentioning

confidence: 99%

The influence of volume fraction of amorphous phase on corrosion resistance of Mg₆₇Zn₂₉Ca₄ alloy

Chlewicka

Cieślak

Mizera

2019

Materials & Corrosion

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The aim of this study was to investigate the structure and corrosion resistance of amorphous, amorphous‐crystalline, and crystalline Mg67Zn29Ca4 alloy for biodegradable applications. This paper presents a preparation method and results of the structural characterization and corrosion resistance analysis of the material. Samples were prepared in the form of 3 mm diameter rods. The structure of the alloy was examined with the use of X‐ray diffractometry and scanning electron microscopy. The thermal properties of the samples were examined with differential scanning calorimetry (DSC). Results of DSC analysis were used to determine heat treatment temperatures, allowing to obtain different fractures of crystalline phase in the material. Corrosion resistance of heat‐treated samples was investigated by immersion tests and electrochemical measurements performed in the simulated body fluid. The X‐ray diffraction results confirmed that the prepared Mg67Zn29Ca4 alloy's structure is fully amorphous. After heat treatment, samples with different fractions of amorphous phase in the structure were obtained. Immersion tests of the samples showed that the structure significantly influenced corrosion resistance in examined materials. It should be pointed out, that certain amounts of crystalline phase in amorphous matrix can greatly improve the corrosion resistance of Mg67Zn29Ca4 alloy.

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“…The change in the current provides the information about the sizes and concentration of the molecules inside the pore, to reveal the dynamics process of the molecules translocation behaviours [3]. Some nanoscale objects can be detected using a nanopore, such as nanoparticles [4–6], viruses [7–9], protein molecules [10–13] and DNA sequences [14–17]. Nanopores are of two types.…”

Section: Introductionmentioning

confidence: 99%

Hydrogen Peroxide Sensing Based on Inner Surfaces Modification of Solid-State Nanopore

Zhu

Liu

2017

Nanoscale Res Lett

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There are many techniques for the detection of molecules. But detection of molecules through solid-state nanopore in a solution is one of the promising, high-throughput, and low-cost technology used these days. In the present investigation, a solid-state nanopore platform was fabricated for the detection of hydrogen peroxide (H2O2), which is not only a label free product but also a significant participant in the redox reaction. We have successfully fabricated silicon nitride (Si3N4) nanopores with diameters of ~50 nm by using a focused Ga ion beam, the inner surface of the nanopore has been modified with horseradish peroxidase (HRP) by employing carbodiimide coupling chemistry. The immobilized HRP enzymes have ability to induce redox reactions in a single nanopore channel. Moreover, a real-time single aggregated ABTS•+ molecular translocation events were monitored and investigated. The designed solid-state nanopore biosensor is reversible and can be applied to detect H2O2 multiple times.Electronic supplementary materialThe online version of this article (doi:10.1186/s11671-017-2190-x) contains supplementary material, which is available to authorized users.

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Translocation of Gold Nanorod Through a Solid-State Nanopore

Cited by 3 publications

References 0 publications

Detection of a single enzyme molecule based on a solid-state nanopore sensor

Detection of a single enzyme molecule based on a solid-state nanopore sensor

The influence of volume fraction of amorphous phase on corrosion resistance of Mg₆₇Zn₂₉Ca₄ alloy

Hydrogen Peroxide Sensing Based on Inner Surfaces Modification of Solid-State Nanopore

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Translocation of Gold Nanorod Through a Solid-State Nanopore

Cited by 3 publications

References 0 publications

Detection of a single enzyme molecule based on a solid-state nanopore sensor

Detection of a single enzyme molecule based on a solid-state nanopore sensor

The influence of volume fraction of amorphous phase on corrosion resistance of Mg67Zn29Ca4 alloy

Hydrogen Peroxide Sensing Based on Inner Surfaces Modification of Solid-State Nanopore

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The influence of volume fraction of amorphous phase on corrosion resistance of Mg₆₇Zn₂₉Ca₄ alloy