Transmission behavior of pNIPAM microgel particles through porous membranes

Pan, Si; Torres, Jenny Mayra Guicela Tzoc; Hoare, Todd; Ghosh, Raja

doi:10.1016/j.memsci.2015.01.033

Cited by 11 publications

(5 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Membrane filtration has also been applied to the separation and purification of colloidal dispersions. , The assemblies are sequentially filtered through membranes with decreased pore size. First of all, it should be stated that fractionation by membrane filtration using mini-extruder is limited by the pore size of membrane.…”

Section: Resultsmentioning

confidence: 99%

Nanoparticle Loading Induced Morphological Transitions and Size Fractionation of Coassemblies from PS-b-PAA with Quantum Dots

et al. 2016

View full text Add to dashboard Cite

Inorganic nanoparticles play a very important role in the fabrication and regulation of desirable hybrid structures with block copolymers. In this study, polystyrene-b-poly(acrylic acid) (PS48-b-PAA67) and oleic acid-capped CdSe/CdS core/shell quantum dots (QDs) are coassembled in tetrahydrofuran (THF) through gradual water addition. QDs are incorporated into the hydrophilic PAA blocks because of the strong coordination between PAA blocks and the surface of QDs. Increasing the weight fraction of QDs (ω = 0-0.44) leads to morphological transitions from hybrid spherical micelles to large compound micelles (LCMs) and then to bowl-shaped structures. The coassembly process is monitored using transmission electron microscopy (TEM). Formation mechanism of different morphologies is further proposed in which the PAA blocks bridging QDs manipulates the polymer chain mobility and the resulting morphology. Furthermore, the size and size distribution of assemblies serving as drug carriers will influence the circulation time, organ distribution and cell entry pathway of assemblies. Therefore, it is important to prepare or isolate assemblies with monodisperse or narrow size distribution for biomedical applications. Here, the centrifugation and membrane filtration techniques are applied to fractionate polydisperse coassemblies, and the results indicate that both techniques provide effective size fractionation.

show abstract

Section: Resultsmentioning

confidence: 99%

Nanoparticle Loading Induced Morphological Transitions and Size Fractionation of Coassemblies from PS-b-PAA with Quantum Dots

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Pan et al . 9 synthesized fluorescently labelled microgels, and found microgels in the permeate when using microporous membranes with pores much smaller than the diameter of the particles. Understanding this transmission mechanism (also in relation to the pore size distribution) is important for process optimization when the presence of particles in the permeate is not desirable, or where a specific size separation is needed.…”

Section: Discussionmentioning

confidence: 99%

“…When using a suspension of colloidal soft particles, clogging can happen through agglomeration or the formation of arches, as was the case for hard particles; but the pore size is no longer the strict gate keeper for particle permeation 7,8 . Soft particles larger than constrictions may be pushed all the way through; 1 whereas the largest particles have highest propensity to get stuck in the constrictions and clog the channels 9 .…”

Section: Introductionmentioning

confidence: 99%

Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions

Meireles

Bouchoux

Schroën

2019

Sci Rep

View full text Add to dashboard Cite

Clogging of porous media by soft particles has become a subject of extensive research in the last years and the understanding of the clogging mechanisms is of great importance for process optimization. The rise in the utilization of microfluidic devices brought the possibility to simulate membrane filtration and perform in situ observations of the pore clogging mechanisms with the aid of high speed cameras. In this work, we use microfluidic devices composed by an array of parallel channels to observe the clogging behavior of micrometer sized microgels. It is important to note that the microgels are larger than the pores/constrictions. We quantify the clog propensity in relation to the clogging position and particle size and find that the majority of the microgels clog at the first constriction independently of particle size and constriction entrance angle. We also quantify the variations in shape and volume (2D projection) of the microgels in relation to particle size and constriction entrance angle. We find that the degree of deformation increases with particle size and is dependent of constriction entrance angle, whereas, changes in volume do not depend on entrance angle.

show abstract

“…Recent studies demonstrate that microgels may be employed efficiently as a support material for constructing responsive nanostructured membranes. , Bell et al synthesized the glycidyl methacrylate (GMA)-functionalized poly( N -isopropylacrylamide- co -acrylic acid) (P(NIPAm- co -AA)) microgel with GMA as a cross-linkable site. The various layers of the microgel were created on a poly(ether sulfone) (PES) microporous membrane support.…”

Section: Introductionmentioning

confidence: 99%

Anti(-bio)fouling Nanostructured Membranes Based on the Cross-Linked Assembly of Stimuli-Responsive Zwitterionic Microgels

Mishra

Biswal

Dubey

et al. 2022

ACS Appl. Polym. Mater.

View full text Add to dashboard Cite

This study embodies the development of a thermoresponsive nanostructured antifouling membrane based on cross-linkable zwitterionic microgels for tunable water filtration and molecular separation applications. The zwitterionic vinylimidazole propane sultone (VIPS) comonomer was synthesized by reacting vinylimidazole with 1,3-propane sultone. The microgels were synthesized utilizing a one-step precipitation polymerization approach by taking 10 and 20 wt % of the VIPS with N-isopropyl acrylamide (NIPAm), 2-aminoethyl methacrylate (AEMA), with the cross-linker N,N′-methylene bis(acrylamide) (BIS) to produce MG-10 and 20, respectively. Various chemical and morphological characterizations were carried out to establish the synthesis and characteristics of microgels. Suction filtration of a dilute MG-20 dispersion was used to construct cross-linked microgel membranes of different thicknesses over a track-etched membrane support in the next step. Surface and morphological analyses validate the packed microgel layer formation. The constructed layer was temperature-switchable, resulting in a twofold increase in water flux from room temperature to 40 °C. The thin and closely packed microgel particles resulted in a sub-2 nm surface pore size, allowing for strong rejection (>99%) of small molecules. Because of the presence of VIPS, both of the microgels displayed excellent anti(-bio)fouling properties against bacterial and protein foulants. The surface demonstrated ultralow protein adsorption and a high flux-recovery ratio (>90%), resulting in antifouling performance. The stability of the cross-linked robust microgel layer without any leaching warrants dimensional stability and long-term permeability. This smart gating membrane with improved anti(-bio)fouling activity expands the scope of thermoresponsive microgel-based nanostructured membranes and has significant potential in water purification and molecular separation applications.

show abstract

Transmission behavior of pNIPAM microgel particles through porous membranes

Cited by 11 publications

References 32 publications

Nanoparticle Loading Induced Morphological Transitions and Size Fractionation of Coassemblies from PS-b-PAA with Quantum Dots

Nanoparticle Loading Induced Morphological Transitions and Size Fractionation of Coassemblies from PS-b-PAA with Quantum Dots

Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions

Anti(-bio)fouling Nanostructured Membranes Based on the Cross-Linked Assembly of Stimuli-Responsive Zwitterionic Microgels

Contact Info

Product

Resources

About