“…Minimizing tissue trauma and subsequent stress response is a goal of surgery [ 42 ] and CRP is often included as an objective marker in studies investigating this response in dogs [ 37 , 42 , 43 , 45 ]. CRP has on several occasions been used in studies investigating new surgical procedures for the veterinary clinic [ 26 , 29 , 31 , 35 ], in studies using dogs as model for human disease [ 27 , 28 , 30 ], and in studies comparing different surgical procedures [ 32 , 34 ]. In the last group several studies have compared surgical trauma by comparing different surgical procedures in different tissues [ 9 , 33 ].…”