Transplantation of adult Schistosoma mansoni from mice to the portal system of Cebus monkeys immunized against the donor host

Coelho, Paulo Marcos Zech; Melo, J.R.C.; Pereira, Leandro de Mattos; Nascimento, Evaldo

doi:10.1016/0035-9203(79)90143-3

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1980

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“…The detection of host antigens on S. mansoni by worm transfer techniques has been reported only for worms grown in mice (Boyer et al 1977;Cioli & Neis, 1972;Coelho et al 1979;Smithers et al 1969). Worms grown in rats (Cioli, 1976) and hamsters (Boyer & Ketchum, 1976;Coelho et al 1976) were not rejected when transferred into recipient hosts immunized against the donor host's r.b.c.…”

Section: Discussionmentioning

confidence: 99%

Schistosoma mansoni: host antigen occurrence on worms recovered from laboratory vertebrate animals

1980

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SUMMARYBy transferring Schistosoma mansoni (12 to 14-day-old worms) from one host into the peritoneal cavity of a host of a different species, it was possible to demonstrate that worms grown in rats, hamsters, Mastomys natalensis and Cebus monkeys were rejected by recipient animals previously immunized against red blood cells of the donor hosts. These results suggest that host-like antigens are acquired by S. mansoni in all hosts. The transfer of worms into the peritoneal cavity has proved to be a simple and convenient method for studying the presence of host antigens in S. mansoni.

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Section: Discussionmentioning

confidence: 99%