2010
DOI: 10.1590/s0365-05962010000300016
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Transplante de melanócitos no piebaldismo: relato de caso

Abstract: Piebaldism is a rare genodermatosis in which depigmented skin areas are unresponsive to topical or light treatment. This article describes the importance of transplant techniques using noncultured melanocytes (minigrafting) in the treatment of piebaldism. Keywords: Melanocytes; Piebaldism; Transplantation Resumo: O piebaldismo é uma genodermatose rara onde as lesões acrômicas não respondem aos tratamentos tópico e fototerápico. Este artigo tem como objetivo demonstrar a importância do transplante de melanócito… Show more

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Cited by 8 publications
(5 citation statements)
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“…5 Neves and collaborators (2010) observed progressive repigmentation with 90% improvement in achromic lesion in the pretibial region after 3 sessions of melanocyte transplantation using the punch grafting technique. 8 Machado-Filho and collaborators (2005) demonstrated moderate to intense degree of pigmentation on vitiligo lesions, by means of a curettage grafting method. 9 …”
Section: Discussionmentioning
confidence: 99%
“…5 Neves and collaborators (2010) observed progressive repigmentation with 90% improvement in achromic lesion in the pretibial region after 3 sessions of melanocyte transplantation using the punch grafting technique. 8 Machado-Filho and collaborators (2005) demonstrated moderate to intense degree of pigmentation on vitiligo lesions, by means of a curettage grafting method. 9 …”
Section: Discussionmentioning
confidence: 99%
“…Recently, transplant of autologous melanocytes obtained through the culture of melanocytes or of melanocytes and keratinocytes has been described as a safe and effective treatment for patients with piebaldism. [2021] This induced scarless repigmentation using a small donor site. After these procedures, phototherapy can be used.…”
Section: Discussionmentioning
confidence: 99%
“…Des essais thérapeutiques chirurgicaux ont été rapportés avec des succès variables [ 3 ], parmi eux, la transplantation autologue d'un nombre de mélanocytes qui peut atteindre 100% de repigmentation, elle consiste en un transfert de mélanocytes par greffe totale ou partielle de la peau, minigrafting ou bulles d'aspiration. Les mélanocytes peuvent également être obtenus par culture des mélanocytes ou des mélanocytes-kératocytes [ 14 ]. La transplantation micropunch (Minigrafting) épidermique totale en utilisant des sites de 1 à 1,25 mm donatrices épidermiques est une méthode relativement peu coûteuse et efficace, mais elle est limitée par les cicatrices du site donneur [ 3 , 14 ].…”
Section: Discussionunclassified
“…Les mélanocytes peuvent également être obtenus par culture des mélanocytes ou des mélanocytes-kératocytes [ 14 ]. La transplantation micropunch (Minigrafting) épidermique totale en utilisant des sites de 1 à 1,25 mm donatrices épidermiques est une méthode relativement peu coûteuse et efficace, mais elle est limitée par les cicatrices du site donneur [ 3 , 14 ].…”
Section: Discussionunclassified