Transport lattice models of heat transport in skin with spatially heterogeneous, temperature-dependent perfusion

Gowrishankar, Thiruvallur R.; Stewart, Donald A.; Martín, Germán Valencia; Weaver, James C.

doi:10.1186/1475-925x-3-42

Cited by 107 publications

(36 citation statements)

References 53 publications

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“…͑8͔͒ values may be estimated using the data reported previously. 22,26 Assuming s = 1.2 g cm −3 , c shs = 3.3 Jg −1 K −1 , b = 1.06 g cm −3 , c shb = 3.77 Jg −1 K −1 , = 1.25 ‫ء‬ 10 −3 m 3 s −1 m −3 tissue, ␣ =6 Wm −2 K −1 , T b = 310 K, T a = 295 K, and T s0 = 306 K for 1 mm thick skin layer, the values can be determined as Ϸ 0.003 s −1 and S 0 Ϸ 0.002 Ks −1 . Both values are within the ranges of the model parameters ͑Table I͒.…”

Section: Discussionmentioning

confidence: 99%

“…The first one deals with heat transport in the skin and the second simplification is the treatment of histamine release by the mast cells after the allergen injection. The heat transfer in the skin has been traditionally addressed using Pennes bioheat equation, 18,22 which accounts for the ability of tissue to transfer heat by both passive conduction and blood perfusion. In most cases, spatially distributed external heating occurs in skin exposed to radiation such as microwave, ultrasound, or laser light.…”

Section: Discussionmentioning

confidence: 99%

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Application of thermography for the assessment of allergen‐induced skin reactions

2011

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It was demonstrated that the thermographic measurements supplemented by the mathematical model offer a new approach to the quantification of allergen-induced skin reactions. Despite the applied simplifications, the proposed model reflected properly the mechanism of heat generation during skin prick test. Moreover, the continuous recording of the skin temperature represents an additional possibility to investigate the mechanism of the allergic reaction.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Application of thermography for the assessment of allergen‐induced skin reactions

2011

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“…Figure 11. Skin resistance R s during the course of the healing process with values for upper and lower limit according to [7], literature value from [9], and value measured at ZAE Bayern for a healthy test person.…”

Section: Discussionmentioning

confidence: 99%

“…Thermophysical properties for different layers of the forearm tissue are given in [9]. Since our model combines these into one thermal layer only, we used mean values for density and specific heat in the simulations as given in The mean thermal conductivity of the forearm, which was assumed to be 20 mm thick, was taken from the measured value of R s .…”

Section: Predicted Thermal Performance Of the Pcm Bandagementioning

confidence: 99%

Phase change material for thermotherapy of Buruli ulcer: modelling as an aid to implementation

Braxmeier

Hellmann²,

Beck

et al. 2009

Journal of Medical Engineering & Technology

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A mathematical model was developed and validated to predict the thermal behaviour of a heat application device based on a phase change material (pcm) for the heat treatment of Mycobacterium ulcerans infection (Buruli ulcer). The thermal model allows the prediction of skin surface temperatures and an optimization of the amount of pcm with respect to discharge time. A first prototype of such a pcm bandage was manufactured and used in a proof-of-principal trial in Cameroon. The experimental data were analysed and yielded no difference in thermoregulatory response between people living in hot or moderate climate. Short-term maximum skin surface temperatures of 42 degrees C are tolerable; the pcm bandage keeps the skin surface temperature above 40 degrees C for about four to five hours. This makes such pcm bandages an ideal device for the heat treatment of Buruli ulcer. The pcm bandage is easy to apply, cheap, and thus is well suited for use in low-resource countries.

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“…The results indicated that the Fourier model under predicted temperatures, compared to the non-Fourier model. Gowrishankar et al (2004) investigated on bio-heat transfer in skin with spatially heterogeneous, temperature-dependent perfusion, using a transport lattice approach. The heat transport processes were modeled using a lattice that represents the Pennes bioheat equation in perfused tissues, and diffusion in non-perfused regions.…”

Section: Non-conventional Theoretical Modelsmentioning

confidence: 99%

Microscale Transport Phenomena for Bio-Engineering Applications: Recent Advances

Sobhan¹,

Thomas²,

Peterson³

2017

JAN

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Abstract. The importance of microscale thermal energy transport has dramatically increased in the past several years and a number of significant investigations have been undertaken to better understand the fundamental phenomena that govern the behavior of energy transport at the microscale. While the original focus of this research was directed towards the thermal management of semiconductor devices and spacecraft thermal control, there has been an increased interest in the thermophysical phenomena occurring in biological systems, and bio-medical devices and applications. As a result a number of investigations have been reported, in which the thermal transport phenomena in microscale systems and passages are of significant importance. In this context, this following attempts to review the relevant literature on the theoretical and experimental investigations of microscale transport phenomena as specifically related to bioengineering and biomedical applications. Modeling methodologies, experimental studies, instrumentation techniques and research leading to the development of optimal bio-medical systems are reviewed and discussed.

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Transport lattice models of heat transport in skin with spatially heterogeneous, temperature-dependent perfusion

Cited by 107 publications

References 53 publications

Application of thermography for the assessment of allergen‐induced skin reactions

Application of thermography for the assessment of allergen‐induced skin reactions

Phase change material for thermotherapy of Buruli ulcer: modelling as an aid to implementation

Microscale Transport Phenomena for Bio-Engineering Applications: Recent Advances

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