Transsphenoidal surgery using a high definition video telescope for pituitary adenomas in dogs with pituitary dependent hypercortisolism: Methods and results

Abstract

Modifications of a trans-oral transsphenoidal technique for surgical removal of pituitary tumors provides a safe and effective strategy for long-term remission of PDH with acceptable morbidity and mortality.

A magnetic resonance imaging‐based classification system for indication of trans‐sphenoidal hypophysectomy in canine pituitary‐dependent hypercortisolism

“…Notably, a new surgical technique involving high‐definition video telescopy was recently developed (Mamelak et al . ). This technique might allow evaluation of the dorsal portions of pituitary tumours and improved complete resection rates in higher‐grade cases.…”

“…, Mamelak et al . ). The pituitary gland height‐to‐cross sectional area of the brain (P/B) value (Kooistra et al .…”

Transsphenoidal surgery: accuracy of an image‐guided neuronavigation system to approach the pituitary fossa (sella turcica)

“…Two localization points are drilled, estimating the location of the pituitary fossa on the basisphenoid bone in the surgical suite, prior to transporting the dog for CT. The surgical approach is then planned on the basis of the 2 localization points in relation to the pituitary fossa on the CT images . This more precise technique increases the surgeon's confidence in correctly locating the pituitary fossa but does take additional time.…”

The Influence of Pituitary Size on Outcome After Transsphenoidal Hypophysectomy in a Large Cohort of Dogs with Pituitary‐Dependent Hypercortisolism

“…Recurrences in dogs with PDH are thought to occur because of regrowth of the pituitary adenoma from microscopic islets of tumor cells left behind during surgery or normal pituitary cells that transform into adenoma cells. Recently, a telescope and high definition camera system with 16× magnification have been used for better visualization during transsphenoidal hypophysectomy in dogs . With this technique, the fossa can be inspected for macroscopic pituitary tissue, that otherwise might be left behind, possibly improving postoperative remission in some patients.…”