Transvaginal ultrasound-guided embryo transfer in IVF

Ultrasound-guided embryo transfer: summary of the evidence and new perspectives. A systematic review and meta-analysis

“…Finally, Karavani et al (2017) carried out a power analysis aimed only at investigating the reduction of patient discomfort in the TV-US group. Considering these limitations and a recently pubished large retrospective study (Larue et al, 2017) describing opposite results (with an advantage for the TV-US technique), we cannot reach a definitive conclusion. It is interesting to note, however, that all the studies (in particular, Karavani et al, 2017) suggested the benefits of TV-US as feasibility (no second operator), better visualization of the uterus and embryo transfer location, and reduction of patient pain, anxiety and discomfort levels (Bodri et al, 2011;Porat et al, 2010).…”

“…Of the 109 relevant manuscripts identified, 59 studies were excluded after examination of the abstracts and 50 studies were further evaluated by retrieving the full text. Finally, after the exclusion of 12 studies, we identified 38 manuscripts (published between 1989 and 2017) eligible for qualitative analysis (Wisanto et al, 1989;Al-Shawaf et al, 1993;Lindheim et al, 1999;Kan et al, 1999;Coroleu et al, 2000;Abdelmassih et al, 2001;Garcıa-Velasco et al, 2001;Kojima et al, 2001;Prapas et al, 2001;Tang et al, 2001;Coroleu et al, 2002;García-Velasco et al, 2002;Matorras et al, 2002;Sallam et al, 2002;Bar Hava et al, 2003;Cruickshank et al, 2003;Marconi et al, 2003;Mirkin et al, 2003;Weissman et al, 2003;de Camargo Martins et al, 2004;Moraga-Sanchez et al, 2004;Li et al, 2005;Maldonado et al, 2005;Flisser et al, 2006;Lambers et al, 2006;Chen et al, 2007;Davar et al, 2007;Kosmas et al, 2007;Drakeley et al, 2008;Eskandar et al, 2008;Zakova et al, 2008;Porat et al, 2010;Bodri et al, 2011;Ammar et al, 2013;Revelli et al, 2016;Saravelos et al, 2016;Karavani et al, 2017, Larue et al, 2017. Qualitative synthesis of the included studies is shown in Tables 1 and 2.…”

“…Only one retrospective trial was available on this topic. Larue et al (2017), in a large retrospective study, found a significant increase in pregnancy rates from a comparison of TV-US (pregnancy rate 38%) with TA-US-guided embryo transfer (pregnancy rate 30%) (P < 0.001) ( Table 2).…”

“…A total of four studies compared TV-US versus TA-US-guided embryo transfer (Bodri et al, 2011;Karavani et al, 2017;Larue et al, 2017;Porat et al, 2010). One study was excluded (Larue et al, 2017) owing to its study design (observational), and three randomized controlled trials were included in the quantitative analysis (Bodri et al, 2011;Karavani et al, 2017;Porat et al, 2010).…”

<p>Progestin-Primed Ovarian Stimulation with Dydrogesterone versus Medroxyprogesterone Acetate in Women with Polycystic Ovarian Syndrome for in vitro Fertilization: A Retrospective Cohort Study</p>

“…Embryo transfer was all conducted via the guidance of abdominal ultrasound in our center, although some evidences are emerging in favor of transvaginal ultrasound. 20,21 Once a pregnancy was achieved, lutealphase support was continued until 10 weeks of gestation.…”