Traqueobroncopatia osteocondroplástica: relato de 2 casos e revisão bibliográfica

Pinto, José; Silva, Luiz Carlos da; Perfeito, Delmer J. P.; Soares, Josemar dos Santos

doi:10.1590/s1808-86942010000600019

Cited by 10 publications

(5 citation statements)

References 14 publications

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“…Aschoff-Freiburg reported changes to the tracheal elastic tissue, and used the term osteoplastic tracheopathy to describe the condition, and similarly, in 1964, Secrest et al labeled it osteoplastic tracheobronchopathy. 3 …”

Section: Discussionmentioning

confidence: 99%

“…4 According to Secrest, it is estimated that only 5% of the cases are diagnosed during the person's life. 3 …”

Section: Discussionmentioning

confidence: 99%

“…4 According to Secrest, it is estimated that only 5% of the cases are diagnosed during the person's life. 3 While most patients with TO are asymptomatic, when symptomatic, common presenting symptoms are chronic cough, dyspnea, wheeze, hemoptysis, and recurrent respiratory tract infections, which often lead to the misdiagnosis of asthma. 5…”

Section: Clinical Features and Presentationmentioning

confidence: 99%

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Tracheobronchopathia osteochondroplastica in the setting of COVID-19

et al. 2022

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Tracheobronchopathia osteoplastica (TO) is a rare, benign disease of unknown etiology, primarily affecting the major tracheobronchial tree, characterized by irregular nodular calcifications of the cartilaginous component of the inner wall of the tracheobronchial tree while sparing the posterior wall, leading to progressive narrowing of the airway. We report the case of a 60-year-old male otherwise healthy nonsmoker, who complained of chronic breathing discomfort and recurrent chest infections and was found to have TO according to radiographic, microlaryngoscopic, and biopsy findings. He experienced a flare up with worsening of disease progression after years of being in stable condition, after his infection with SARS-CoV-2.

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Section: Discussionmentioning

confidence: 99%

“…4 According to Secrest, it is estimated that only 5% of the cases are diagnosed during the person's life. 3 …”

Section: Discussionmentioning

confidence: 99%

Section: Clinical Features and Presentationmentioning

confidence: 99%

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Tracheobronchopathia osteochondroplastica in the setting of COVID-19

et al. 2022

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“…Reports from overseas showed that there was no significant difference in the prevalence of TO between males and females [7]. It was also reported that the prevalence of TO between males and females was about 3 : 1 [8]. In China, there was no significant difference regarding the prevalence of TO between males and females in most studies [2].…”

Section: Discussionmentioning

confidence: 99%

“…e first case of TO was recorded abroad in 1855. It was reported that there was no significant difference in the prevalence rate between men and women [7], while others reported that the prevalence rate was about 3 : 1 for men and women [8]. e pathogenesis of TO is unknown, which may be related to congenital tracheobronchial dysplasia, long-term physical, chemical, or mechanical stimulation, chronic inflammation, and metabolic disorders [6].…”

Section: Introductionmentioning

confidence: 99%

Clinical Characteristics of Six Cases of Tracheobronchopathia Osteochondroplastica

Guo

Zhou

Wei

et al. 2020

Canadian Respiratory Journal

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Objective. To investigate the clinical characteristics of tracheobronchopathia osteochondroplastica (TO). Methods. The clinical data of six patients with TO from November 2016 to November 2018 were retrospectively analyzed. The etiology, clinical manifestations, diagnosis, and treatment of TO were summarized. Result. All six patients with TO were middle-aged males, confirmed by histopathological examination. The main clinical symptoms were cough, sputum, hemoptysis, chest pain, and repeated pulmonary infection. Some patients could make a preliminary diagnosis by chest CT, and bronchoscopy showed that TO mainly occurred in the trachea and the main bronchus and was more likely to invade the right bronchus. The treatment mainly includes anti-infection, phlegm-resolving, and other symptomatic treatment. Conclusion. TO is a benign disease predisposing to adults, and males are more likely to be affected. Its clinical manifestations are lack of specificity, and the cause may be related to chronic infection. Bronchoscopy combined with histopathological examination is the primary approach for the diagnosis of TO. There is no well-recognized treatment standard for TO, and the judgment of therapeutic effect is inconsistent. It is necessary to improve the understanding of this disease from a clinical perspective.

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