Tratamento da mucosite oral com laser de baixa potência: revisão sistemática de literatura

Abstract

Verificar qual o melhor protocolo de aplicação da laserterapia de baixa potência para prevenção e tratamento da mucosite oral químio e rádio induzida. Revisão sistemática de literatura sobre laserterapia na prevenção e tratamento da mucosite oral rádio e químio induzida. Foram utilizadas as indexações “mucositis”, “lowpower laser therapy”, na busca de estudos clínicos randomizados dos últimos 10 anos nas bases de dados de referência: PubMed, LILACS e Cochrane Library. A pesquisa resultou em 16 estudos clínicos randomizados sobre laserterapia de baixa potência, sendo consenso a aplicação 5 vezes por semana, com densidade de energia variada entre 1,3 e 6,0 J/cm². O presente estudo identificou que a laserterapia reduz o tempo de cicatrização e os graus de mucosite oral, apesar de ainda serem necessários mais estudos para definir o protocolo de atuação. Palavras-chave: Estomatite. Mucosite. Quimioterapia. Radioterapia. Terapia a laser de baixa intensidade.

Cuidados bucais de pacientes oncológicos pediátricos e o uso da laserterapia no tratamento de mucosites

“…Currently, laser therapy has been used in several areas of dentistry due to its technology that provides greater comfort to patients and reliability to the professional. 14,35,36 The studies by Albuquerque, Moraes and Sobral (2007) are in agreement with Cavalcante, Barros and Catão (2011) and Fiorentino et al (2015), reiterating the advantages of using LLLT, which according to these authors provides relief of acute and chronic pain, promoting immediate and temporary analgesia; It may also be incorporated in the treatment of oral mucositis, herpes, aphthous lesions, candidiasis, neuralgia, xerostomia, facial palsy, joint pain, inflammation and lesions in the oral mucosa, dentinal hypersensitivity, tem-poromandibular disorders, periodontal disorders, restorative, orthodontic and endodontic treatments, post-surgical moment and headache.…”

“…29 The use of the He-Ne low-level laser (632.8nm, 60mW, 2J/ cm2) applied daily before each radiotherapy session for seven weeks is a simple and non-traumatic technique for the prevention and treatment of mucositis of various origins, being able to reduce the severity and duration of oral mucositis associated with radiotherapy. 29,34,35 Studies performed by Bensadoun et al (1999) have shown a reduction in pain and an improvement in ingestion ability. The treatment is painless, little invasive (performed in the patient's oral cavity), low cost, and provides fast and safe application, with studies that prove its efficacy in the pro-phylaxis and treatment of oral mucositis as well as of various other organic disorders.…”

“…The treatment is painless, little invasive (performed in the patient's oral cavity), low cost, and provides fast and safe application, with studies that prove its efficacy in the pro-phylaxis and treatment of oral mucositis as well as of various other organic disorders. 34,35 Therapeutic effects of laser therapy The therapeutic properties of lasers have been studied since their discovery, and their analgesic action has been observed particularly on the forms of chronic pain of various etiopathogens, from peripheral receptors to central nervous system stimulation. Therefore, when laser light interacts with cells and tissue at the appropriate dose, certain cellular functions may be stimulated, such as lymphocyte stimulation, mast cell activation, increased mitochondrial ATP production, and proliferation of various types of cells.…”

Atendimento odontológico de paciente submetido à radioterapia em região de cabeça e pescoço: relato de caso clínico

“…A mucosite oral é outra manifestação bucal que se inicia aproximadamente 15 dias após o começo da radioterapia; consiste em um dano à mucosa oral e ao trato gastrointestinal, apresentando-se em graus variados de eritema e podendo evoluir para ulcerações. Uma das alternativas terapêuticas para a mucosite oral é a laserterapia de baixa potência, um tratamento não invasivo que promove rápida cicatrização e analgesia 12,13 .…”

Copaiba Oral Hydrogel for Oral Mucositis Control - Search Note

“…Despite the various therapeutic possibilities available, the best protocol to be used should consider the specific needs of each patient and the cost-benefit ratio [8][9][10] . So, from this reality, this unpublished study proposed to create and test the Copaíba-based Oral Hydrogel, after approval of the project by the Research Ethics Committee (Approval Protocol: 2.143.119) whose partial result is exemplified below in this case report.…”