Tratamiento endoscópico del reflujo de vesicoureteral en pediatría: Experiencia preliminar con la inyección subureteral de coaptite®

Durban, Miguel Julián Mora; Sebastián, Francisco Javier Navarro; Delgado, María Belén Muñoz; González, J.I. García; Andrés, Pedro Dionisio Paniagua

doi:10.4321/s0004-06142006000500006

Cited by 6 publications

(2 citation statements)

References 28 publications

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“…The primary center success rate reported by Mevorach et al is similar to the European single-center studies of CaHA, which have shown 70–80% success rates after two injections [8, 10, 11]. …”

Section: Discussionsupporting

confidence: 75%

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A Comparison of Calcium Hydroxyapatite and Dextranomer/Hyaluronic Acid for the Endoscopic Treatment of Vesicoureteral Reflux

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Wong

Kennedy

2013

Advances in Urology

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Purpose. Minimal data exists comparing dextranomer/hyaluronic acid (Dx/HA) and calcium hydroxyapatite (CaHA) for the endoscopic treatment of VUR in the hands of a single user. Materials and Methods. We reviewed our consecutive single-user case series of 27 children (42 ureters) receiving endoscopic treatment with CaHA and 21 children (33 ureters) who received Dx/HA injection. Children receiving CaHA injections were divided into two groups of 13 and 14 patients (Coaptite I and II) to assess the learning curve effects. Postoperatively, RBUS and VCUG were performed. Multiple regression analysis was performed to assess statistical significance of success rates. Results. The total CaHA group had a per-ureter success rate (Grade 0) of 52% after one injection. When separated into two cohorts, the single injection per-ureter success rates were 43% for Coaptite I and 62% for Coaptite II. In contrast, the Dx/HA series had a single injection per-ureter success rate (Grade 0) of 78%. Conclusions. Our consecutive case experience shows improved results for Dx/HA compared to CaHA, though the learning curve effects and evolution of injection technique likely played a role in the improved outcomes in the Dx/HA cohort. A randomized controlled multicenter trial would provide the most accurate data comparing these two agents.

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Section: Discussionsupporting

confidence: 75%

“…Multiple authors have described a significant frequency of late failures regardless of whether Dx/HA or CaHA was used [11, 13–15]. Most of these studies showed failures at 1 year but not much further beyond that.…”

Section: Discussionmentioning

confidence: 99%

A Comparison of Calcium Hydroxyapatite and Dextranomer/Hyaluronic Acid for the Endoscopic Treatment of Vesicoureteral Reflux

Ngo

Wong

Kennedy

2013

Advances in Urology

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Injectable synthetic calcium hydroxylapatite ceramic microspheres (Coaptite) for passive fecal incontinence

Ganio¹,

Marino²,

Giani³

et al. 2008

Tech Coloproctol

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Combination of calcium hydroxyapatite and autologous blood for endoscopic treatment of vesicoureteral reflux in children

et al. 2014

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Tratamiento endoscópico del reflujo de vesicoureteral en pediatría: Experiencia preliminar con la inyección subureteral de coaptite®

Abstract: Resumen.-OBJETIVO: Analizar nuestra experiencia en el tratamiento endoscópico del reflujo vesicoureteral (RVU) en pediatría, mediante la inyección subureteral de hidroxiapatita cálcica (Coaptite®

Cited by 6 publications

References 28 publications

A Comparison of Calcium Hydroxyapatite and Dextranomer/Hyaluronic Acid for the Endoscopic Treatment of Vesicoureteral Reflux

A Comparison of Calcium Hydroxyapatite and Dextranomer/Hyaluronic Acid for the Endoscopic Treatment of Vesicoureteral Reflux

Injectable synthetic calcium hydroxylapatite ceramic microspheres (Coaptite) for passive fecal incontinence

Combination of calcium hydroxyapatite and autologous blood for endoscopic treatment of vesicoureteral reflux in children

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