Traumatic brain injury

O'Keefe, Kraigher

doi:10.1002/9781118990810.ch30

Cited by 4 publications

(5 citation statements)

References 37 publications

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“…[13] In addition, brain injuries that damage the pituitary gland and hypothalamus and underlying medical conditions such as diabetes mellitus can also cause hyperglycemia. [14,15] This study's average body mass index (BMI) in headinjured patients was 24.15 kg/m2. Based on previous research, BMI does not have a significant relationship with the type and severity of head injury or the prognosis or outcome of head injury.…”

Section: Resultsmentioning

confidence: 90%

Correlation Between Hyperglycemia and Length of Stay in Severe Head Injury Patients at Prof. Dr. Igng Ngoerah Hospital

Permana¹,

Maliawan²,

Niryana³

et al. 2023

International Journal of Scientific Advances

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Background: Head injury is one of the emergency cases in surgery that is often found in the emergency. From year to year, cases of head injuries have significantly increased. High blood glucose levels in head-injured patients are thought to correlate with the level of consciousness, especially in patients with severe head injuries. The severe head injury affects the various complications that occur, which affects the length of stay (LOS) in the hospital. Objectives: To determine the correlation between hyperglycemia and length of stay in patients with severe head injuries. Methods: This study is an analytical observational study with a prospective design. The research sample included patients with severe head injuries who came to the surgical emergency unit at Prof. Dr. IGNG Ngoerah Hospital and met the inclusion criteria in medical record data throughout November 2019 – April 2020, with 56 samples. Results: The mean random blood sugar measurement results were found to be higher in the LOS ≥7 days group (210.14±83.93 mg/dL) compared to the LOS group7 days (165.88±92.44 mg/dL). Multivariate analysis using logistic regression found a significant relationship between mean hyperglycemia and LOS in patients with severe head injuries (OR 7.46; 95% CI [1.839-30.300]; P = 0.005) Conclusion: There is a significant correlation between mean hyperglycemia and the length of stay in patients with severe head injuries at Prof. Dr. IGNG Ngoerah Hospital.

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Section: Resultsmentioning

confidence: 90%

Correlation Between Hyperglycemia and Length of Stay in Severe Head Injury Patients at Prof. Dr. Igng Ngoerah Hospital

Permana¹,

Maliawan²,

Niryana³

et al. 2023

International Journal of Scientific Advances

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“…In the study results, the majority of subjects were male82,42%, with the ratio of men: to women being 4:1; this is to the incidence of TBI in Indonesia and abroad. There are more men than women, with an incidence of up to 2 times the percentage difference than women [12]. This incident proves that the large number of activities that cause TBI in men is due to high mobility in men as a result of work demands, social life, which requires most men to do activities outside the home by using vehicles, and low awareness when driving to maintain road safety [13].…”

Section: Discussionmentioning

confidence: 92%

High Serum S100B Protein Levels As A Predictor Of Cognitive Function Disorders In Moderate Traumatic Brain Injury Patients

Jayanthi¹,

Laksmidewi²,

Gelgel³

et al. 2023

International Journal of Scientific Advances

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Objective: To prove high serum S100B protein levels as a predictor of impaired cognitive function in patients with moderate traumatic brain injury. Method: A prospective cohort analytic observational study. The subjects are patients with a moderate degree of TBI with inclusion criteria: onset of TBI 24 hours, age 17-40 years old, and the exclusion criteria were the presence of impaired cognitive function pre-traumatic brain injury (Short IQCODE) 3), depression and multiple trauma. Patients/families/guardians who agreed to the informed consent were checked for S100B levels at <24 hours, then matched with the Montreal Cognitive Assessment version Indonesia (MoCA-INA) questionnaire on day 14 after TBI. This study’s data analysis consisted of univariate and bivariate analysis using Chi-Square. The significance level is stated with p <0.05, 95% confidence interval (CI) assisted by the IBM SPSS version 23. Results: There were 43 research subjects; 23 in the high S100B group and 20 in the S100B group were not high. The mean age is 28 years, with a ratio of 4:1 for men and females. Most of the years, education ≥12 years. The incidence of cognitive dysfunction in patients with moderate traumatic brain injury in the high serum S100B group was 76.19%, while in the non-high serum S100B group was 23.80%, with RR = 6.85, with 95% CI between 1.78-26 .36, and p-value = 0.005. Conclusion: High serum S100B protein levels as a predictor of cognitive function disorders were statistically significant in moderate traumatic brain injury patients with a risk of 6.85 times.

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“…For example, men have higher TBIs than women, which might be related to societal roles and high engagement in risky activities. [15][16][17][18] As with TBI registries in other countries, the majority of patients sustained mild TBI. 8,17 Prior studies have found that many survivors of TBI have cognitive and physical symptoms, further contributing to the large body of evidence that even mild TBI is associated with long-lasting problems of functioning, especially among young children.…”

Section: Discussionmentioning

confidence: 99%

“…[15][16][17][18] As with TBI registries in other countries, the majority of patients sustained mild TBI. 8,17 Prior studies have found that many survivors of TBI have cognitive and physical symptoms, further contributing to the large body of evidence that even mild TBI is associated with long-lasting problems of functioning, especially among young children. 8,19,20 Injuries to internal organs 0(0) 0(0) 0(0) 4 The results suggest that falls are the leading cause of TBI, while road traffic injuries rank first in mortality, which is similar to the findings from the published studies conducted in Northern Europe and the United States.…”

Section: Discussionmentioning

confidence: 99%

“…8,19,20 Injuries to internal organs 0(0) 0(0) 0(0) 4 The results suggest that falls are the leading cause of TBI, while road traffic injuries rank first in mortality, which is similar to the findings from the published studies conducted in Northern Europe and the United States. 8,17,[19][20][21] The high incidence of fall-related TBIs among hospitalized patients highlighted the need for effective prevention strategies especially among children, that will be targeted to reducing indoor and outdoor hazards as well as minimizing risk-taking activities. 22 Road traffic injury is the leading cause of TBI in LMICs, while in Georgia, despite the sharp growth of the road infrastructure over the last years, these are only in the 3rd place.…”

Section: Discussionmentioning

confidence: 99%

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Epidemiology of Traumatic Brain Injury in Georgia: A Prospective Hospital-Based Study

Burkadze

Axobadze

Chkhaberidze

et al. 2021

RMHP

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Purpose: Traumatic brain injury (TBI) is one of the major causes of morbidity and mortality worldwide, disproportionally affecting low-and middle-income countries (LMICs). Epidemiological characteristics of TBI at a national level are absent for most LMICs including Georgia. This study aimed to establish the registries and assess causes and outcomes in TBI patients presenting to two major trauma hospitals in the capital city-Tbilisi. Patients and Methods: The prospective observational study was conducted at Acad. O. Gudushauri National Medical Center and M. Iashvili Children's Central Hospital from March, 1 through August, 31, 2019. Patients of all age groups admitted to one of the study hospitals with a TBI diagnosis were eligible for participation. Collected data were uploaded using the electronic data collection tool-REDCap, analyzed through SPSS software and evaluated to provide detailed information on TBI-related variables and outcomes using descriptive statistics. Results: Overall, 542 hospitalized patients were enrolled during the study period, about 63% were male and the average age was 17.7. The main causes of TBI were falls (58%) and struck by or against an object (22%). The 97% suffered from mild TBI (GCS 13-15). Over 23% of patients arrived at the hospital more than 1 hour after injury and 25% after more than 4-hours post-injury. Moderate and severe TBI were associated with an increased hospital length of stay. Mortality rate of severe TBI was 54%. Conclusion: This study provides important information on the major epidemiological characteristics of TBI in Georgia, which should be considered for setting priorities for injury management.

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Traumatic brain injury

Cited by 4 publications

References 37 publications

Correlation Between Hyperglycemia and Length of Stay in Severe Head Injury Patients at Prof. Dr. Igng Ngoerah Hospital

Correlation Between Hyperglycemia and Length of Stay in Severe Head Injury Patients at Prof. Dr. Igng Ngoerah Hospital

High Serum S100B Protein Levels As A Predictor Of Cognitive Function Disorders In Moderate Traumatic Brain Injury Patients

Epidemiology of Traumatic Brain Injury in Georgia: A Prospective Hospital-Based Study

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