2010
DOI: 10.1038/sj.bdj.2010.295
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Traumatic chemical oral ulceration: a case report and review of the literature

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Cited by 56 publications
(54 citation statements)
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“…The alkalis dissolve the proteins and collagens, leading to the saponification of the fatty tissue and to liquefactive necrosis. The saponification and liquefactive necrosis do not limit the tissue penetration, so compared to acids, alkalis have the potential to cause more extensive damage and to allow deeper penetration of the chemicals . The most common lesions are chemical burns; the more the toxic agents persist its action impairing the healing process, these lesions evolve to ulcers, bone necrosis, or even fistulas (Table ).…”
Section: Discussionmentioning
confidence: 99%
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“…The alkalis dissolve the proteins and collagens, leading to the saponification of the fatty tissue and to liquefactive necrosis. The saponification and liquefactive necrosis do not limit the tissue penetration, so compared to acids, alkalis have the potential to cause more extensive damage and to allow deeper penetration of the chemicals . The most common lesions are chemical burns; the more the toxic agents persist its action impairing the healing process, these lesions evolve to ulcers, bone necrosis, or even fistulas (Table ).…”
Section: Discussionmentioning
confidence: 99%
“…Most of the suicide attempts with chemicals involve the aerodigestive tract due to the swallowing of hazardous substances. Oral lesions may occur, but the most damaged tissues are found in organs with the longer exposure periods; this damage ranges in severity from mild to fatal …”
Section: Discussionmentioning
confidence: 99%
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“…Such ulcers may have been present for several weeks and may be deep crater-like lesions with rolled edges which are indurated on palpation because of surrounding fibrosis. [12] Another cause might be the topical application of some drugs, like aspirin, that determinates chemical burns, dose-and time-related. The reactions vary in severity from oedema through to necrosis of the epithelium.…”
Section: Discussionmentioning
confidence: 99%