Traumatic Events and Substance Use Disorders in Adolescents

Basedow, Lukas A.; Kuitunen‐Paul, Sören; Roessner, Veit; Golub, Yulia

doi:10.3389/fpsyt.2020.00559

Cited by 34 publications

(30 citation statements)

References 37 publications

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“…Internal consistency of the instrument was large for the present sample (Cronbach's α = 0.84, n = 51 adolescents with complete item data) and in a previous work of our group (Cronbach's α = 0.87, n = 114 adolescent SUD outpatients) [43].…”

Section: Substance Use Disorder Severitysupporting

confidence: 51%

Comparing self-report and parental report of psychopathologies in adolescents with substance use disorders

Kuitunen‐Paul

Eichler

Wiedmann

et al. 2021

Eur Child Adolesc Psychiatry

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Both internalizing and externalizing psychopathologies interfere with the treatment of substance use disorders (SUD) in adolescents. Self-reports of psychopathologies are likely biased and may be validated with parental reports. We compared N = 70 standardized self-reports of adolescents entering outpatient SUD treatment (13.2–18.6 years old, 43% female) to parental reports on the same psychopathologies, and explored biases due to gender, age, SUD diagnoses and SUD severity. Bivariate bootstrapped Pearson correlation coefficients revealed several small to moderate correlations between both reporting sources (r = 0.29–0.49, all pcorrected ≤ 0.039). A repeated measures MANOVA revealed moderately stronger parental reports of adolescent psychopathologies compared to adolescent self-reports for most externalizing problems (dissocial and aggressive behaviors, p ≤ 0.016, η2part = 0.09–0.12) and social/attention problems (p ≤ 0.012, η2part = 0.10), but no differences for most internalizing problems (p ≥ 0.073, η2part = 0.02–0.05). Differences were not associated with other patient or parental characteristics including age, gender, number of co-occurring diagnoses or presence/absence of a certain SUD (all puncorrected ≥ 0.088). We concluded that treatment-seeking German adolescents with SUD present with a multitude of extensive psychopathologies. The relevant deviation between self- and parental reports indicate that the combination of both reports might help to counteract dissimulation and other reporting biases. The generalizability of results to inpatients, psychiatry patients in general, or adolescents without SUD, as well as the validity of self- and parental reports in comparison to clinical judgements remain unknown.

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Section: Substance Use Disorder Severitysupporting

confidence: 51%

Comparing self-report and parental report of psychopathologies in adolescents with substance use disorders

Kuitunen‐Paul

Eichler

Wiedmann

et al. 2021

Eur Child Adolesc Psychiatry

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“…Veterans were found to have a higher risk of suffering from many major chronic diseases (i.e., circulatory, nervous, digestive, musculoskeletal, or respiratory diseases) after the war ( 13 ). Studies also shown that adolescents those who experienced stressful events may be worse school performance or have worse health conditions ( 14 ). The subsequent long-term physiological changes, especially inflammatory function disorders, may lead to a decline in overall health and an increase in diseases emergence and even death.…”

Section: Traumatic Stress Disorder May Cause Changes In the Body's Physiological Functionsmentioning

confidence: 99%

The Relationship Between Inflammation and Post-traumatic Stress Disorder

Sun

Zhu

2021

Front. Psychiatry

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Background: Stress disorders, such as post-traumatic stress disorder (PTSD), are attracting much attention. However, the relationship between traumatic stress and inflammation is rarely discussed.Subjects and Methods: As studies have linked PTSD to altered susceptibility to various diseases, such a psychiatric condition may lead to long-term systematic changes in physiological functions. We searched PubMed with the keywords “traumatic stress,” “stress disorders,” “post-traumatic stress disorder,” and “inflammation.”Results: Based on 65 previously published studies, we reviewed the long-term effects of PTSD, as well as traumatic events, on inflammatory function from both epidemiological and biological perspectives. Post-traumatic stress disorder is related to the immune response, including an increase in inflammatory factors and a reduction in anti-inflammatory factors. Additionally, it has been demonstrated that traumatic stress disorder and immune disease share a common genetic basis at the gene expression level.Conclusions: Understanding this relationship is of great significance for optimizing treatment plans for patients with PTSD.

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“…Furthermore, this study is the first published psychometric assessment of the German version of the DUDIT. While previous studies in German adults (Schäfer et al, 2017;Spencer et al, 2018;Dyba et al, 2019) and German adolescents (Basedow et al, 2020) have used the DUDIT as a measure or screening tool, none have reported on the psychometric properties. Additionally, previous research has assessed the DUDIT on basis of the DSM-IV criteria for substance abuse and dependence (see Hildebrand, 2015 for an overview), which makes this study the first psychometric assessment using the updated DSM-5 criteria with three levels of SUD.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy of the Drug Use Disorder Identification Test and Its Short Form, the DUDIT-C, in German Adolescent Psychiatric Patients

et al. 2021

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BackgroundA common screening instrument for substance use disorders (SUDs) is the Drug Use Disorders Identification Test (DUDIT) which includes a short form regarding only drug consumption (DUDIT-C). We aim to assess if a German version of the DUDIT, adapted for adolescents, is a suitable screening instrument in a sample of adolescent psychiatric patients.MethodsN = 124 (54 female) German adolescent (M = 15.6 + 1.5 years) psychiatric patients completed the DUDIT and received a diagnostic interview (MINI-KID) assessing DSM-5 SUD criteria. A confirmatory factor analysis (CFA), receiver operating characteristic (ROC) curves, the area under the curve (AUC), and Youden’s Index were calculated.ResultsA two-factor model of the DUDIT shows the best model fit (CFI = 0.995, SRMR = 0.055, RMSEA = 0.059, WRMR = 0.603). The DUDIT as well as the DUDIT-C show high diagnostic accuracy, with AUC = 0.95 and AUC = 0.88, respectively. For the DUDIT a cut-off value of 8.5 was optimal (sensitivity = 0.93, specificity = 0.91, J = 0.84), while for the DUDIT-C the optimal cut-off value was at 1.5 (sensitivity = 0.86, specificity = 0.84, J = 0.70).ConclusionThis is the first psychometric evaluation of the DUDIT in German, adolescent psychiatric outpatients, using the DSM-5 diagnostic criteria. The DUDIT as well as the DUDIT-C are well suited for use in this population. Since in our sample only few patients presented with a mild or moderate SUD, our results need to be replicated in a sample of adolescents with mild SUD.

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Traumatic Events and Substance Use Disorders in Adolescents

Cited by 34 publications

References 37 publications

Comparing self-report and parental report of psychopathologies in adolescents with substance use disorders

Comparing self-report and parental report of psychopathologies in adolescents with substance use disorders

The Relationship Between Inflammation and Post-traumatic Stress Disorder

Diagnostic Accuracy of the Drug Use Disorder Identification Test and Its Short Form, the DUDIT-C, in German Adolescent Psychiatric Patients

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