Traumatic neuroma following sagittal split osteotomy of the mandible

Abstract

A 16-year-old male underwent bilateral sagittal split osteotomy of the mandible to correct a mandibular deficiency. Twenty-one years later, a routine panoramic radiograph revealed a radiolucent lesion on the left side of the mandible. The lesion was biopsied. As the patient did not have symptoms and the lesion was connected to the inferior alveolar nerve, the lesion was not totally excised in order to preserve nerve function. The histological features were consistent with traumatic neuroma, and no further surgical procedure was planned.

The vascularized sural nerve graft based on a peroneal artery perforator for reconstruction of the inferior alveolar nerve defect

“…In the head and neck area, neuromas primarily appear in soft tissue or the auditory nerve, and intraosseous neuromas in the mandible are rare . Treatment of intraosseous neuroma is challenging, and several procedures have been reported to prevent recurrence of the disease.…”

Radiographic Enlargement of Mandibular Canal as an Extranodal Primary Non-Hodgkin’s Lymphoma Early Sign in an Asymptomatic Patient

“…Other hypotheses were multiple endocrine neoplasia type 2b [21] with bilateral mandibular canal involvement and arteriovenous malformation [22]. Unilateral or localized intramandibular canal lesions such as solitary neurofibromas [29, 30], traumatic neuroma of the inferior alveolar nerve [31], localized hypertrophic neuropathy (intraneural perineurioma) [32], vascular leiomyoma [23], and schwannomas were excluded [15] after CT examination. Extranodal NHL was not considered at first, due to its frequency at mandible, or even malignant pathologies, because of the radiographic features.…”

Neuroma traumático em nervo alveolar inferior: relato de caso

“…Exitem poucos relatos de neuromas traumáticos na literatura, dessa forma descritos como uma patologia rara 1,3,9 . A sua etiopatogenia é uma resposta exagerada devido a alguma injuria ao nervo, na maioria dos casos após trauma direto ou manipulação cirúrgica, e não são considerados verdadeiras neoplasias em origem 13 .…”

“…Neuroma traumático não é um neoplasma verdadeiro, mas sim uma proliferação reacional do tecido neural após transecção ou dano de um feixe nervoso¹. Depois de um nervo ser danificado ou lesionado, a porção proximal tenta regenerar-se e reestabelecer a inervação do segmento distal pelo crescimento de axônios atraves de tubulos de células proliferantes de Shawann 1,2,3 . Se estes elementos regeneradores encontram um tecido cicatricial ou por outro lado não podem reestabelecer a inervação, pode se desenvolver uma massa semelhante a um tumor no local da injúria 1,[4][5][6] .…”