Treating infertility: current affairs of cross-border reproductive care

Simopoulou, Mara; Sfakianoudis, Konstantinos; Giannelou, Polina; Pierouli, Aikaterini; Rapani, Anna; Maziotis, Evangelos; Galatis, Dionysios; Bakas, Panagiotis; Vlahos, Nikolaos; Pantos, Konstantinos; Koutsilieris, Michael

doi:10.1515/med-2019-0026

Cited by 9 publications

(6 citation statements)

References 41 publications

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“…On another note, the concept of delaying aging has been intensively promoted in media. This reality reinforces 120 . Staying true to their hippocratic oath "first do no harm" practitioners are invited to see beyond the hype and hope entailed in cutting-edge treatments.…”

Section: Discussionmentioning

confidence: 60%

“…On another note, the concept of delaying aging has been intensively promoted in media. This reality reinforces 120 .…”

Section: Discussionmentioning

confidence: 60%

“…A critical assessment providing a comparative perspective between all novel approaches, regarding issues of importance to the practitioner from cost and practical aspects of application, to novelty, ethical concerns raised, and potential for acquiring future clinical routine practice status is provided in Table 7. Despite the variation considering the respective legal framework regarding application of novel approaches in ART, patients may have access to such treatments enabled by cross-border reproductive care 120 . Staying true to their hippocratic oath "first do no harm" practitioners are invited to see beyond the hype and hope entailed in cutting-edge treatments.…”

Section: Cell Transplantationmentioning

confidence: 99%

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Novel Approaches in Addressing Ovarian Insufficiency in 2019: Are We There Yet?

Sfakianoudis¹,

Rapani

Grigoriadis

et al. 2020

Cell Transplant

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Ovarian insufficiency is described as a multifaceted issue typically encountered in the field of assisted reproduction. The three main identified diagnoses of ovarian insufficiency include premature ovarian failure (POF), poor ovarian response (POR), and advanced maternal age (AMA). Patient heterogeneity in the era of individualized medicine drives research forward leading to the emergence of novel approaches. This plethora of innovative treatments in the service of adequately managing ovarian insufficiency is called to undertake the challenge of addressing infertile patients exploring their reproductive options. This review provides an all-inclusive presentation and critical analysis on novel treatments that have not achieved routine clinical practice status yet, but have recently emerged as promising. In light of the lack of randomized controlled trials conveying safety and efficiency, clinicians are left puzzled in addressing the “how” and “for whom” these approaches may be beneficial. From ovarian injection employing platelet-rich plasma (PRP) or stem cells to artificial gametes and ovaries, ovarian transplantation, and mitochondrial replacement therapy, this descriptive review provides insight toward assisting the practitioner in decision making regarding these cutting-edge treatments. Biological mechanisms, invasiveness levels, efficiency, as well as possible complications, the current status along with bioethical concerns are discussed in the context of identifying future optimal treatment.

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Section: Discussionmentioning

confidence: 60%

“…On another note, the concept of delaying aging has been intensively promoted in media. This reality reinforces 120 .…”

Section: Discussionmentioning

confidence: 60%

Section: Cell Transplantationmentioning

confidence: 99%

See 1 more Smart Citation

Novel Approaches in Addressing Ovarian Insufficiency in 2019: Are We There Yet?

Sfakianoudis¹,

Rapani

Grigoriadis

et al. 2020

Cell Transplant

Self Cite

View full text Add to dashboard Cite

show abstract

“…Some recipients resort to the emerging sector of cross-border reproductive services (CBRS) as a means of broadening the range of fertility options available to them, including the choice between anonymous and non-anonymous donations for their ART treatment ( Bergmann, 2011 ). The desire to use an anonymous donor is reported as one of the possible motivations influencing the decision to consider the use of CBRS ( Rodino et al, 2014 ; Hertz et al, 2016 ; Simopoulou et al, 2019 ). A rising online market facilitating contact between potential sperm donors and recipients in an informal setting beyond institutional and state regulations provides potential self-insemination recipients with opportunities to freely exercise and negotiate their preferences concerning donor (non-)anonymity, the extent of information on the donor, and the level of involvement with the donor, thus circumventing legal restrictions and blurring “the distinction between categories of ‘anonymous’, ‘known’ and ‘identity release’ donations” ( Jadva et al, 2018 :112).…”

Section: Introductionmentioning

confidence: 99%

A Systematic Review of Qualitative Studies Investigating Motives and Experiences of Recipients of Anonymous Gamete Donation

Bauer

2022

Front. Sociol.

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The decision to use an anonymous gamete donation in fertility treatment could have significant long-term psychological and social effects for all stakeholders involved. In light of the growing recognition of donor-conceived children’s right to know their genetic parentage, this entails profound ethical implications. This review aims to carve out the full spectrum of recipients’ motives and experiences related to donor anonymity which could serve as an analytical framework for future ethical and sociological research on issues of donor anonymity. This review was conducted following a seven-step approach for systematic reviews of empirical bioethics literature. The characteristics and quality of the studies included in this review were reported. Data analysis was conducted using qualitative content analysis and was informed by sociological functionalist theorizations of ignorance. The 53 studies selected showed a diverse spectrum of characteristics concerning date and country of study, methodology, family type of participants, sample size, and the timing of data collection in relation to the stage of treatment. A total of 22 categories of motives and experiences of recipients concerning donor anonymity were identified inductively and grouped into five main categories. Donor anonymity was identified as a eufunctional form of ignorance, by which the recipients experienced or intended to control, regulate, or protect inter-stakeholder relations. Interpreting recipients’ motives and experiences concerning donor anonymity as a form of ignorance directed toward particular stakeholders helps reframe the discourse on donor anonymity. It is a fruitful approach that can be refined further and applied in future research. This review identified possible directions for future investigations on motives for donor anonymity: the need for more thorough inquiries into the change in recipients’ preferences over time, such as in the form of longitudinal studies and research on the perspective of non-biological parents.

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“…Over the past decade, literature has addressed diverse treatments and travel routes. [8][9][10][11][12][13] Yet as Kaspar (p.125) notes, 14 'research on medical travel has hitherto largely underestimated cancer' . The lacunae is surprising given the prognosis of cancer increases demand for timely, effective and, what are perceived as, higher quality treatments.…”

Section: Introductionmentioning

confidence: 99%

Scoping the literature on patient travel abroad for cancer screening, diagnosis and treatment

Lunt

Fung

2021

Health Planning & Management

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The incidence of cancer is on the rise globally. Under particular circumstances, patients are willing to travel abroad for healthcare treatments. We know relatively little however about patients travelling overseas for cancer-related screening, diagnosis and treatment. Where do patients go, for what treatments, what are their motivations, decision-making processes and treatment experiences? What do we know about patient safety and risk, and outcomes? More broadly, what are the ethical and legal implications? This review presents the first published assessment of what we term 'transnational oncology treatment' , defined as patients travelling overseas or across borders for cancer screening, diagnosisand treatment. The review undertakes detailed search and retrieval of the literature, using an accepted scoping review method. We present a narrative review of existing knowledge and themes, identifying coverage and gaps. There is a five-fold agenda for future investigation: trajectories and itineraries; in depth focus on treatment decisions, experiences and outcomes; locating patient travel within wider health system analysis; exploration of professional perspectives and coordination; and situating travel within the context of health trade. Such an agenda is multidisciplinary and wide-ranging, encompassing epidemiology, health econom-

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Treating infertility: current affairs of cross-border reproductive care

Cited by 9 publications

References 41 publications

Novel Approaches in Addressing Ovarian Insufficiency in 2019: Are We There Yet?

Novel Approaches in Addressing Ovarian Insufficiency in 2019: Are We There Yet?

A Systematic Review of Qualitative Studies Investigating Motives and Experiences of Recipients of Anonymous Gamete Donation

Scoping the literature on patient travel abroad for cancer screening, diagnosis and treatment

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