Treatment of acne scars with fractional CO₂ laser at 1‐month versus 3‐month intervals: An intra‐individual randomized controlled trial

Abstract

Fractional CO2 laser resurfacing improves atrophic acne scars and a treatment interval of either 1-month or 3-months does not seem to influence the improvement of scar atrophy nor the occurrence of postoperative adverse effects.

Acne scarring: A review of available therapeutic lasers

“…At baseline, the mean severity of both groups was 5.86. There was no significant difference between treatment regimens, as severity scores reduced to 1.82 in the 1 month interval group and to 1.56 in the 3 months group ( P > 0.05) .…”

“…As a result, post‐procedure erythema, edema, bleeding, crusting, infection, and scarring are less of a concern than with ablative fractional lasers (Fig. ) . However, like other non‐ablative lasers, multiple treatment sessions are necessary.…”

“…This was compared to an increase of 23% increase when using the 585 nm PDL [50]. Negishi et al showed increases in both collagen and elastin in the papillary dermis after treatment with IPL using either a 550 or 570 nm filter [52].…”

Efficacy of MAS063DP lotion vs 0.02% triamcinolone acetonide lotion in improving post‐ablative fractional CO2 laser resurfacing wound healing: a split‐face, triple‐blinded, randomized, controlled trial

“…The inflammation causing the production of arachidonate‐derived chemical mediators from the cell membrane components, such as prostaglandin (PG) E2, leukotrienes (LT) C4, and thromboxanes (TX) B2, may be responsible for the induction of PIH and could stimulate the melanocyte by accelerating melanin production and melanosome transferring process . Thus, topical steroid with anti‐inflammatory effect can be effective in preventing post‐AFL complications …”

Fractional carbon dioxide laser resurfacing of skin grafts: long‐term results of a prospective, randomized, split‐scar, evaluator‐blinded study

“…Fractional laser therapy has been intensively investigated over the past few years [1][2][3][4][5][6]. Many controlled clinical trials have proven the efficacy of fractional CO 2laser resurfacing for treating photoaged skin and rhytides [7,8], atrophic acne scars [9][10][11] as well as postoperative and traumatic atrophic scars [12]. No randomized controlled studies are yet available on the treatment of hypertrophic scars, but there is evidence that fractional CO 2 -laser resurfacing may also be effective in treating this type of scar [13,14].…”