Treatment of Bovine Schistosomiasis With Medicinal Plant Veronia Anthelmintica (Kaliziri), an Alternative Approach

Abstract

Background: Veronia anthelmintica (Kaliziri) is a medicinally very important plant as being reported for remarkable therapeutic potential. The
 present research evaluates its antischistosomal activity.
 Methods and Materials: 54 buffaloes naturally infected with Schistosomiasis were used for anthelmintic trails. All animals for the study were
 tagged so as to distinguish from others. The animals were checked up on routine basis by a veterinary doctor. Preparation of samples of herbal
 drug and experiment was design according to available literature.
 Results: During present studies, buffalos naturally infected with Schistosomiasis were treated with Veronia anthelmintica (Kaliziri), with dose
 75 mg/kg, 150 mg/kg and 225 mg/kg body weight respectively, and their impact on various parameters like eggs reduction, milk production,
 weight gain and feed intake was noted. Furthermore, their efficiency (%) was compared with standard drug “Praziquantel” (allopathic drug) at
 “10mg/Kg” body weight dose level. The effectiveness (%) of “Praziquantel” was noted as hundred after first dose, while the effectiveness for the
 herbal drug get to this level after injecting of second dose of “225mg/kg body weight”. Statistically significant (P

Anthelmintic Agents from African Medicinal Plants: Review and Prospects

“…contortus and related gastrointestinal nematodes (GIN) of small ruminants are the most widely investigated organisms in in vivo models, whereas sheep and goats are the major animals in which such clinical investigations have been reported [86,87,111,112]. Tere are few reports involving trials in pigs, chickens, goldfsh, snails, rats, and mice [113][114][115][116][117]. Te ability of test substances to reduce faecal egg count (FEC), a typical measure of efects on fecundity, and postmortem intestinal worm burden are the parameters measured in in vivo assays.…”