Treatment of canine generalized demodicosis associated with hyperadrenocorticism with spot-on moxidectin and imidacloprid

Huang, Hui; Lien, Yu-Hsin

doi:10.1186/1751-0147-55-40

Cited by 7 publications

(4 citation statements)

References 17 publications

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“…Adult‐onset demodicosis also exists and is comparable to the demodicosis seen in other species. In the dog, this was reported to be associated with diseases or drugs leading to a compromised immune system such as leishmaniosis, hyperadrenocorticism, hypothyroidism, neoplasia, babesiosis, ehrlichiosis, and glucocorticoid treatment or chemotherapy . Although one report mentioned atopic dermatitis as a frequent concurrent disease, many dogs had received glucocorticoid therapy .…”

Section: Pathogenesismentioning

confidence: 99%

Diagnosis and treatment of demodicosis in dogs and cats

Mueller¹,

Rosenkrantz²,

Bensignor³

et al. 2020

Veterinary Dermatology

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Background Demodicosis is a common disease in small animal veterinary practice worldwide with a variety of diagnostic and therapeutic options. Objectives To provide consensus recommendations on the diagnosis, prevention and treatment of demodicosis in dogs and cats. Methods and materials The authors served as a Guideline Panel (GP) and reviewed the literature available before December 2018. The GP prepared a detailed literature review and made recommendations on selected topics. A draft of the document was presented at the North American Veterinary Dermatology Forum in Maui, HI, USA (May 2018) and at the European Veterinary Dermatology Congress in Dubrovnik, Croatia (September 2018) and was made available via the World Wide Web to the member organizations of the World Association for Veterinary Dermatology for a period of three months. Comments were solicited and responses were incorporated into the final document. Conclusions In young dogs with generalized demodicosis, genetic and immunological factors seem to play a role in the pathogenesis and affected dogs should not be bred. In old dogs and cats, underlying immunosuppressive conditions contributing to demodicosis should be explored. Deep skin scrapings are the diagnostic gold standard for demodicosis, but trichograms and tape squeeze preparations may also be useful under certain circumstances. Amitraz, macrocyclic lactones and more recently isoxazolines have all demonstrated good efficacy in the treatment of canine demodicosis. Therapeutic selection should be guided by local drug legislation, drug availability and individual case parameters. Evidence for successful treatment of feline demodicosis is strongest for lime sulfur dips and amitraz baths.

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Section: Pathogenesismentioning

confidence: 99%

Diagnosis and treatment of demodicosis in dogs and cats

Mueller¹,

Rosenkrantz²,

Bensignor³

et al. 2020

Veterinary Dermatology

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“…A case of persistent demodicosis has been reported in an immunocompetent patient whose other comorbidities included metabolic syndrome (diabetes mellitus, hypertension, and hyperlipidemia) and hidradenitis suppurativa 14 . Similarly, a number of case reports exist in the veterinary literature in which persistent, generalized demodicosis is described in immunocompetent animals with endocrine disorders 15,16 . Collectively, these data suggest that some combination of anatomic alterations, endocrine derangements and/or immune system deficiencies collectively exert an effect on the cutaneous microbiome that favors colonization/overgrowth of Demodex spp.…”

Section: Discussionmentioning

confidence: 97%

Symptomatic vulvar demodicosis: A case report and review of the literature

2020

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Demodex folliculorum is a mite that commonly inhabits the pilosebaceous units of facial skin, particularly in a perioral and periorbital distribution. While typically an incidental and asymptomatic parasite, Demodex spp. are proposed to contribute to the pathogenesis of facial folliculitis, chronic blepharitis and papulopustular rosacea. Reports of demodicosis in anatomic locations other than the face are exceedingly rare. Here we report a 36-year-old woman with symptomatic Demodex spp. infesta

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“…Імідоклоприд використовується у багатьох галузях та комбінаціях як інсектицидна діюча речовина, що й обумовлює ефективність застосування при блошиній інвазії (Huang & Lien, 2013;Qureshi et al, 2015).…”

Section: таблицяunclassified

Effectiveness of the immidacloprid/ivermectin combination for external application (“MEGA STOP” for cats)

Sapko

2020

SMLNUVMB

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Diseases of the skin, inflammation, complications of suppurative processes can be caused by invasion of akariformes and lead to the deterioration of animal health, slimming and intoxication. The aim of this work was to investigate the efficacy of the drug “MEGA STOP” by analyzing the clinical status of the animals and the dynamics of hematological parameters. It was used 15 animals aged from 8 months to 5 years, of both sexes. Examined the General condition of the animals (behavior, reaction to external stimuli, presence of appetite, skin and coat, the color of the mucous membranes and the like). It was performed microscopic examination of scrapings from the affected skin and ears, as well as clinical analysis of blood. The drugs were applied according to the instructions and the invasion of intact skin. In all animals with a flea in a single treatment was effective. The blood counts were normal (the upper and lower lime), except for erythrocytes (below normal from 4.72 % to 2.26 %). It was established, that all animals treated with the drug MEGA STOP at 0 day was deviation in the norm of the indicator red blood cells to decrease from 0.4 of 7.36 %. In the following days of the study (10 and 20 day), indicators are normalized and the condition of the animals improved. The maximum deviation of the blood parameters from the norm were detected in an animal with double invasion (otodectosis and fleas). The study of the animals before treatment were violations of the skin in the affected areas of agents, anemia, leukocytosis and eosinophilia. These changes of the blood, characteristic of allergic and intoxication metabolites acariformes. After the first treatment the condition of the ears and skin, according to the results of clinical examination and microscopy, have improved as the blood counts. After the second treatment the animals of both groups a swab from the ears clean and no clinical manifestations. The high efficacy of the drug “MEGA STOP” for the prevention and treatment of flea infestations and acarosan (notoedres, otodectosis in, demodicosis) in single/double skin applied depending on the degree of infestation.

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Treatment of canine generalized demodicosis associated with hyperadrenocorticism with spot-on moxidectin and imidacloprid

Cited by 7 publications

References 17 publications

Diagnosis and treatment of demodicosis in dogs and cats

Diagnosis and treatment of demodicosis in dogs and cats

Symptomatic vulvar demodicosis: A case report and review of the literature

Effectiveness of the immidacloprid/ivermectin combination for external application (“MEGA STOP” for cats)

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