Treatment of chronic urinary salmonella carriers

Bassily, S.; Farid, Z.; Lehman, Jr Js; Kent, Donald C.; Sanborn, Warren R.; Hathout, S

doi:10.1016/0035-9203(70)90013-1

Transactions of the Royal Society of Tropical Medicine and Hygi

1970

DOI: 10.1016/0035-9203(70)90013-1

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Treatment of chronic urinary salmonella carriers

S. Bassily

Z. Farid

Jr Js Lehman

et al.

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1972

1981

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Cited by 18 publications

(1 citation statement)

References 15 publications

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“…Ampicillin given orally four times daily at a dose of 100 mg/kg per day for 4 weeks has been shown to be successful in treating chronic salmonelluria (1), and 250 mg of amoxicillin given orally four times daily for 4 weeks was found to be equally effective (5). This study compares the effectiveness of ampicillin and amoxicillin when given at the same dose of 250 mg twice daily for 4 weeks.…”

mentioning

confidence: 94%

Chronic Salmonella bacteriuria with intermittent bacteremia treated with low doses of amoxicillin or ampicillin

Bassily¹,

Kilpatrick²,

Farid³

et al. 1981

Antimicrob Agents Chemother

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Amoxicillin and ampicillin were compared at a dose of 250 mg twice daily for 4 weeks to treat Salmonella typhi or Salmonella paratyphi A chronic bacteriuria with intermittent bacteremia. Eleven patients received amoxicillin, and 15 received ampicillin. Concentrations of the two drugs were measured in the urine and serum on treatment days 1, 2, and 7. The urine levels of both antibiotics were maximal 2 h after administration, and minimal levels were 80-fold higher than the S. typhi minimal inhibitory concentration and 20-fold higher than the S. paratyphi A minimal inhibitory concentration. The serum level of amoxicillin was below the minimal inhibitory concentration of S. paratyphi A 6 h after administration on each of the testing days. The serum antibiotic levels of the two drugs showed no cumulative effect at day 2 or day 7. Of the 11 patients treated with amoxicillin, 1 had positive urine cultures during treatment, and 1 treated with ampicillin continued to be symptomatic. Recurrence of bacteriuria occurred in three of seven patients with persistent bladder calcification. None of the 26 patients in this study had positive blood culture during or after treatment. Amoxicillin and ampicillin at a dose of 250 mg twice daily were equally successful in treating chronic salmonelluria.

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mentioning

confidence: 94%

Chronic Salmonella bacteriuria with intermittent bacteremia treated with low doses of amoxicillin or ampicillin

Bassily¹,

Kilpatrick²,

Farid³

et al. 1981

Antimicrob Agents Chemother

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show abstract

Studies on the effects of bacteria on experimental schistosome infections in animals

Ottens¹,

Dickerson

1972

Transactions of the Royal Society of Tropical Medicine and Hygi

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Rheumatoid factors in Salmonella and Schistosoma infections

Lehman

Higashi

Bassily

et al. 1972

Transactions of the Royal Society of Tropical Medicine and Hygi

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Treatment of chronic urinary salmonella carriers

Cited by 18 publications

References 15 publications

Chronic Salmonella bacteriuria with intermittent bacteremia treated with low doses of amoxicillin or ampicillin

Chronic Salmonella bacteriuria with intermittent bacteremia treated with low doses of amoxicillin or ampicillin

Studies on the effects of bacteria on experimental schistosome infections in animals

Rheumatoid factors in Salmonella and Schistosoma infections

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