Treatment of Degenerative-Dystrophic Diseases of the Knee Joint Based on the use of Mesenchymal Stem Cells of the Synovial Membrane

Abstract

Using autologous mesenchymal stem cells, 12 patients with pathology of the knee joint cartilage were successfully treated. At the first stage, all patients underwent traditional arthroscopic knee debridement, during which a sample of the synovium was taken, after which the sample was transferred to the National Center for Biotechnology for the cultivation of mesenchymal stem cells. After culturing a therapeutically effective number of cells, the material was punctured into the cavity of the affected joint. Evaluation of the results demonstrated a positive effect of the method on the course of the disease.