Treatment of Dermatitis Herpetiformis With Colchicine

Silvers, David N.; Juhlin, Einer A.; Berczeller, Peter H.; McSorley, John

doi:10.1001/archderm.1980.01640360047016

Cited by 51 publications

(13 citation statements)

References 8 publications

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“…Beneficial effects have been ob served in the therapy of psoriasis [23], Beh cet syndrome [24], necrotizing vasculitis [25], dermatitis herpetiformis [26], pustulo sis of the palms and soles [27] and relapsing polychondritis [28],…”

Section: Discussionmentioning

confidence: 99%

Colchicine Treatment of Urticarial Vasculitis

Werni¹,

Schwarz²,

Gschnait³

1986

Dermatology

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A patient with clinically and histologically typical urticarial vasculitis has been treated with 0.5 mg of colchicine three times per day. This treatment resulted in both disappearance of urticarial skin lesions and amelioration of severe systemic symptoms such as abdominal pain, fever and arthralgia. Colchicine is proposed as an effective therapeutic agent for urticarial vasculitis if other drugs are ineffective, poorly tolerated or contraindicated.

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Section: Discussionmentioning

confidence: 99%

Colchicine Treatment of Urticarial Vasculitis

Werni¹,

Schwarz²,

Gschnait³

1986

Dermatology

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“…Dermatitis herpetiformis [26] Linear IgA disease [27] Epidermolysis bullosa acquisita [28] Chronic Bullous Dermatosis of Childhood [29] Vasculitis: Leucocytoclastic vasculitis (LCV) and Urticarial vasculitis [30] Scleroderma [31] Amyloidosis [32][33][34] Miscellaneous [35][36][37][38][39][40][41][42][43][44][45][46][47] phagocytosis, colchicine may increase superoxide scavenging activity of neutrophils which is impaired in this syndrome.…”

Section: Treatment Of Acute Gout and Familial Mediterranean Fevermentioning

confidence: 99%

Colchicine in dermatology

Konda

Rao

2010

Indian J Dermatol Venereol Leprol

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“…Patients with dermatitis herpetiformis were treated with oral colchicine at a dose between 1.2–2.4 mg/day with at least partial success in three of the four patients in a study by Silvers et al 22 …”

Section: Indicationsmentioning

confidence: 99%

Colchicine Revisited

Bhat

Naguwa

Cheema

et al. 2009

Annals of the New York Academy of Sciences

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Purified from a Mediterranean plant nearly two centuries ago, colchicine has been discovered to inhibit many steps in the inflammatory process. The drug has good oral bioavailability and some enterohepatic recirculation, requiring dose adjustments for kidney disease and avoidance in liver disease. Toxicities are primarily gastrointestinal, hepatic, and hematologic. Colchicine is approved by the U.S. Federal Drug Administration for the treatment and prophylaxis of gout flares but has also been tried with varying success in the treatment of familial Mediterranean fever, primary biliary cirrhosis, psoriasis, Behçet's disease, aphthous stomatitis, linear IgA dermatosis, relapsing polychondritis, Sweet's syndrome, scleroderma, amyloidosis, leukocytoclastic vasculitis, epidermolysis bullosa, and dermatomyositis.

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Treatment of Dermatitis Herpetiformis With Colchicine

Cited by 51 publications

References 8 publications

Colchicine Treatment of Urticarial Vasculitis

Colchicine Treatment of Urticarial Vasculitis

Colchicine in dermatology

Colchicine Revisited

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