Treatment of dermatophytosis in young cattle with propolis and Whitfield's ointment

Çam, Y.; Koc, A. Nedret; Silici, Sibel; Güneş, Vehbi; Buldu, H.; Onmaz, A. C.; Kasap, Filiz

doi:10.1136/vetrec.165.2.57

Cited by 16 publications

(10 citation statements)

References 18 publications

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“…Previous works have already shown the antifungal activity of propolis against dermatophytesin dogs, cows and rabbits [4] [11]; also, its in vitro activity against Trichophyton mentagrophytes has been noted in several studies [12]. Furthermore, the present work not only succeed in demonstrating the effectiveness of propolis for the treatment of dermatophytosis in horses caused by Trichophyton, but also proved its viability as an effective treatment for skin infections caused by Candida albicans.…”

Section: Discussionsupporting

confidence: 68%

“…Once these substances have been removed from the skin's surface, a better residual activity from the propolis contained in the ointment is achieved. A similar study on dermatophytosis in cows was conducted by [11], wherein he mentions that better results are obtained when the application of propolis-based ointment is combined with the application of another oitment that contains benzoic and salicylic acids, instead of using one product alone.…”

Section: Discussionmentioning

confidence: 89%

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Use of Mexican Propolis for the Topical Treatment of Dermatomycosis in Horses

Rodríguez¹,

Monteagudo²,

Orozco³

et al. 2016

OJVM

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Five horses with lesions compatible with dermatomycosis were selected and skin scrapings were taken from all affected areas. Samples were then treated with 10% KOH and observed by direct microscopic examination; fungal cultures using Mycobiotic Agar and Borelli Agar were also preformed; Trichophyton mentagrophytes was identified in two cases, whereas Candida albicans was identified in the other three. Skin lesions in cases 1 and 2 were treated topically with ketoconazol ointment, while in the remaining cases a weekly bath with propolis-based shampoo and application of propolis-based ointment on the lesions 2 to 3 times a week were implemented. Treatment in all cases lasted 4 weeks. Pictures were taken before and after treatment and, making use of the Image Pro-Express ® software, therapy efficacy was determined by measurement of lesion area diameter and a significant reduction in lesion size was observed by the end of the 4 weeks of treatment with ketoconazole and propolis-based products. Thus proving the effectiveness of such propolis-based products, making them a natural therapeutic alternative for the treatment of cutaneous mycoses in horses, and carrying none of the toxic side effects of conventional pharmaceuticals.

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Section: Discussionsupporting

confidence: 68%

Section: Discussionmentioning

confidence: 89%

Use of Mexican Propolis for the Topical Treatment of Dermatomycosis in Horses

Rodríguez¹,

Monteagudo²,

Orozco³

et al. 2016

OJVM

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“…4,14 It can also be used in veterinary medicine to treat canine fungal otitis and dermal mycosis infections as well as bovine dermatophytosis. 15,16 Propolis is also an ingredient of cosmetic creams and lotions. It can be used in shampoos and hair lotions, acne treatments, shaving products, deodorants, antiperspirants, as well as antidandruff and sebum-stabilising agents.…”

Section: Introductionmentioning

confidence: 99%

Determination and Quantification of Gallic Acid in Raw Propolis by High-performance Liquid Chromatography–Diode Array Detector in Burundi

Nyandwi

Kılıç

Çeli̇k³

et al. 2019

EASci

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Background: Honey, pollen, and propolis are among the products that bees process and derive from plants and flowers. Propolis is a resinous material that bees gather from the buds and bark of some trees and small plants. Propolis from temperate climates mainly contains phenolic compounds, in contrast with propolis from tropical climates, which mainly contains terpenes. This study aimed to determine, characterise, and quantify the phenolic content of raw propolis from Burundi. Methods: In this study, a total of 6 samples were collected from the provinces of Rumonge, Cibitoke, and Ruyigi in Burundi. Fifteen phenolic compounds (caffeic acid, ferulic acid, epigallocatechin gallate, isoferulic acid, cinnamic acid, caffeic acid phenethyl ester, gallic acid, apigenin, chrysin, galangin, quercetin, kaempherol, rutin trihydrate, naringenin, and pinocembrin) were used as high-performance liquid chromatography (HPLC) standards for qualitative and quantitative analyses of the propolis samples. Results: Among the 15 phenolic compounds checked, only 1 -gallic acid -was detected at a measurable level using an HPLC-diode array detector system. Conclusion: In addition to terpenes, propolis found in sub-Saharan Africa may contain phenolic compounds. Further advanced investigation of sub-Saharan African propolis is required for more detailed characterisation.

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“…Use of several veterinary drugs on food-producing animals, grown intensively by modern animal husbandry practices, is common to many countries (Mellon et al, 2001;Solomon et al, 2002;Wachtel et al, 2002;Goldman 2004 andCam et al, 2009). Thiabendazole (TBZ), registered in many countries, is used as a broadspectrum anthelminthic agent to control parasitic infestations in animals.…”

Section: Introductionmentioning

confidence: 99%

Accumulation and Degradation of Thiabendazole Residues in Eggs in Administered Layer Hens

Naika¹,

Khanum²

2014

Sci. Technol. Arts Res. J.

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Article Information Administration of thiabendazole (TBZ) to laying hens may cause accumulation of the drug residues in eggs. Twenty five week old hens (n=6) were administered with a single oral dose of 75 mg TBZ/day/layer hen for 5 consecutive days and its residues in eggs were quantified by HPLC-FD. The highest TBZ (0.4308±0.0253 ppm), below maximum residue limit (0.0886±0.0161 ppm) and below limit of detection (LOD) residue concentrations in eggs were observed on mean time of 127.54, 177.62 and 252.58 h after first feeding, respectively. The highest TBZ concentration (0.5260 ppm) and total residue on any day from 2 to 9 day in the entire egg white portion were significantly (P<0.01) higher than those in the yolk. The highest residue concentrations as well as the highest total residue in egg albumin (0.5944 ppm), yolk (0.6587 ppm) and whole egg (0.5867 ppm) were quantified. The highest TBZ concentration (0.5260 ppm) as well as total TBZ residue on any day from day 2 to day 9 in the entire white portion of egg were significantly (P<0.01) higher than those in the yolk. Egg white, yolk and whole egg from the TBZ fed hens had residues at 50.71 to 153.50, 75.62 to 153.50 and 50.71 to 153.50 h after first feeding, respectively. The highest concentration TBZ residue in whole egg is 0.4308±0.0253 ppm and cumulative residue is 8.1886±6.5385 ppm and also calculated in microgram is useful to show as per the standard values. The work indicated that safe dose and days to consume egg. Safe time/days can be reduced for consuming eggs after administration of thiabendazole by using different types of decontamination techniques.

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Treatment of dermatophytosis in young cattle with propolis and Whitfield's ointment

Cited by 16 publications

References 18 publications

Use of Mexican Propolis for the Topical Treatment of Dermatomycosis in Horses

Use of Mexican Propolis for the Topical Treatment of Dermatomycosis in Horses

Determination and Quantification of Gallic Acid in Raw Propolis by High-performance Liquid Chromatography–Diode Array Detector in Burundi

Accumulation and Degradation of Thiabendazole Residues in Eggs in Administered Layer Hens

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