Treatment of Facial Skin Using Combinations of CO2, Q-Switched Alexandrite, Flashlamp-Pumped Pulsed Dye, and Er:YAG Lasers in the Same Treatment Session

Manuskiatti, Woraphong; Fitzpatrick, Richard; Goldman, Mitchel P.

doi:10.1046/j.1524-4725.2000.98159.x

Cited by 65 publications

(43 citation statements)

References 36 publications

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“…Epidermal melanin and melanocytes are competing chromophores for dermal pigment laser therapy and increase the risk of post-inflammatory hyperpigmentation. By performing treatment sessions at short intervals, more photons can target the dermal chromophores through the hypopigmented epithelium while avoiding scattering of the beam 12 . In addition, heat has little effect on the hypopigmented epidermis, thereby preventing PLH 13 .…”

Section: Discussionmentioning

confidence: 99%

Q-Switched Nd:YAG Laser Therapy of Acquired Bilateral Nevus of Ota-like Macules

et al. 2009

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Background: Acquired bilateral nevus of Ota-like macules (ABNOM) is a dermal pigmented lesion common in individuals of Oriental origin. The Q-switched Nd:YAG laser (QSNYL) has been used successfully to treat a variety of benign, dermal, pigmented lesions, including nevus of Ota lesions. The similarity between ABNOM and nevus of Ota suggested that QSNYL may also be effective in the former. Objective: To determine the efficacy and side-effect profiles of QSNYL treatment of ABNOM in Korean patients. Methods: Of 42 Korean patients with ABNOM, 29 were treated with QSNYL (1,064 nm, 3 mm spot size, fluence 8∼ 9.5 J/cm 2 ), for up to 10 sessions each. Clinical photographs were taken before and after treatment. Lesion clearance was graded and complications such as hyperpigmentation, scarring, hypopigmentation, and erythema were assessed. Results: Of the 29 treated patients, 19 (66%) showed excellent or good results. Of the patients who were treated more than 3 times, 76% showed good to excellent results. Two patients experienced post-laser hyperpigmentation (PLH), which persisted for more than one month, but no patient experienced persistent erythema or hypertrophic scarring. Conclusion: QSNYL is safe and effective in the treatment of ABNOM in Korean patients. Short-interval repetitive treatment is especially useful in improving therapeutic results and reducing PLH.

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Section: Discussionmentioning

confidence: 99%

Q-Switched Nd:YAG Laser Therapy of Acquired Bilateral Nevus of Ota-like Macules

et al. 2009

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“…Blinded investigators also assessed degree of improvement in infraorbital hyperpigmentation, while subjects completed a satisfaction questionnaire, on day 60. The presence and severity of treatment-related adverse events were recorded on a 5-point scale (none [0], trace [1], mild [2], moderate [3], and severe [4]). …”

Section: Outcome and Statistical Analysismentioning

confidence: 99%

“…This multifactorial etiology often necessitates a multimodal therapeutic approach including volume restoration and laser stimulated increase in dermal collagen and epidermal thickness [2][3][4][5][6]. Hyperpigmentation of the delicate undereye skin can be especially problematic to treat due to the potential for mixed pigmentation presentation (hemosiderin vs. melanin) and the propensity toward post-inflammatory hyperpigmentation especially in darker skin types.…”

Section: Introductionmentioning

confidence: 99%

Prospective studies of the efficacy and safety of the picosecond 755, 1,064, and 532 nm lasers for the treatment of infraorbital dark circles

et al. 2017

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Background: Infraorbital dark circles result from a combination of factors. The fractionated picosecond 755 nm alexandrite laser and dual wavelength picosecond Nd:YAG laser have not been examined as a method of addressing infraorbital hyperpigmentation. Objective: To determine the efficacy and safety of treatment of infraorbital dark circles using fractionated picosecond 755 nm and dual wavelength picosecond Nd:YAG laser. Methods and Materials: These trials did not utilize a comparative design; rather, these were separate, prospective, open-label, evaluator-blinded trials utilizing two treatment regimens: (i) 19 adult subjects were treated in a single session with the dual wavelengths of 532 nm and 1,064 nm in consecutive passes using the fractionated lens; (ii) 10 adult subjects were treated using the picosecond 755 nm laser via the fractionated lens in three treatment sessions at 3 week intervals. Subjects in both studies were followed-up for blinded-investigator assessment of infraorbital hyperpigmentation, adverse events, and improvement compared to baseline. Results: The dual wavelength picosecond Nd:YAG laser, blinded-investigator assessment did not demonstrate a significant improvement in infraorbital hyperpigmentation at day 60 (P ¼ 0.16). The picosecond 755 nm alexandrite laser significantly improved infraorbital hyperpigmentation by day 42, with improvement maintained through day 132 (P ¼ 0.07 and 0.00001, respectively). Adverse events were mild and temporary. Conclusion: A single treatment with the fractionated picosecond 1,064/532 nm lasers did not produce a significant improvement in infraorbital hyperpigmentation. A series of three treatments with the fractionated picosecond 755 nm laser resulted in significant improvement in hyperpigmentation.

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“…As patients grow older, loss of the subcutaneous periorbital fat and skin atrophy may lead to unveiling of the orbital vasculature. The bluish color is secondary to the visible dermal capillary network 11 (Fig. 3a,b).…”

Section: Superficial Location Of Vasculaturementioning

confidence: 99%

“…Despite the great number of available topical medications and creams to attenuate dark circles, there are no evidence‐based studies to support their use. In the last decade, laser and intense pulsed light are increasingly being used in cosmetic dermatology 11 …”

Section: Treatmentmentioning

confidence: 99%

What causes dark circles under the eyes?

Freitag

Cestari

2007

J of Cosmetic Dermatology

109

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Dark circles under the eyes (DC) are defined as bilateral, round, homogeneous pigment macules on the infraorbital regions. Despite its significant prevalence, there are a few published studies about its pathogenesis. DC are caused by multiple etiologic factors that include dermal melanin deposition, postinflammatory hyperpigmentation secondary to atopic or allergic contact dermatitis, periorbital edema, superficial location of vasculature, and shadowing due to skin laxity. The purpose of this review is to discuss some of the available evidences about the anatomic features that could explain dark circles and the proposed treatments for this unpleasant condition.

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Treatment of Facial Skin Using Combinations of CO2, Q-Switched Alexandrite, Flashlamp-Pumped Pulsed Dye, and Er:YAG Lasers in the Same Treatment Session

Abstract: For patients who present with multiple cosmetic complaints, combined treatment using appropriate lasers offers excellent therapeutic outcome.

Cited by 65 publications

References 36 publications

Q-Switched Nd:YAG Laser Therapy of Acquired Bilateral Nevus of Ota-like Macules

Q-Switched Nd:YAG Laser Therapy of Acquired Bilateral Nevus of Ota-like Macules

Prospective studies of the efficacy and safety of the picosecond 755, 1,064, and 532 nm lasers for the treatment of infraorbital dark circles

What causes dark circles under the eyes?

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