Treatment of Fecal Incontinence With a Rechargeable Sacral Neuromodulation System: Efficacy, Clinical Outcome, and Ease of Use—Six-Month Follow-Up

Jottard, Katleen; Broeck, Sylvie Van den; Komen, Niels; Bruyninx, Luc; Wachter, Stefan De

doi:10.1111/ner.13298

Cited by 11 publications

(5 citation statements)

References 13 publications

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“…The Axonics® rechargeable SNM device was implanted in 15 patients who were asked to report FI episodes and quality of life in their bowel diary. The results show that the rechargeable SNM system was indeed effective in treating patients with FI: at just four weeks, 13 patients reported ≥50% decrease in FI episodes-decreasing from a median of 8 (5.8-20.3) to 1.5 (0.4-4.5) weekly episodes [14]. Additionally, no adverse effects were reported and the overall scores for patient satisfaction using the symptom-related quality of life (QoL) survey, FISI and participant satisfaction questionnaire were high in all marks; those that were particularly outstanding include role limitations due to physical health problems, role limitations due to personal or emotional problems, and social functioning [14].…”

Section: Axonicsⓡ Devicementioning

confidence: 89%

Use of New Rechargeable Battery and MRI-Friendly Technologies in Sacral Neuromodulation Systems to Treat Fecal Incontinence

J¹,

Csuka²,

Ghoniem³

2020

JJGH

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Sacral neuromodulation (SNM) is a minimally invasive therapeutic technique that has been used to effectively treat overactive bladder and bowel dysfunction. There have been, however, several obstacles with standard, non-rechargeable SNM devices such as frequent battery replacement and complications with the conditional safety for full-body Magnetic Resonance Imaging (MRI). Recently, rechargeable and MRI-friendly technologies have been introduced into SNM devices to be used in the treatment of fecal incontinence. Though rechargeable batteries have been utilized recently for treating overactive bladder and urinary dysfunction, the implementation of these new technologies into the treatment of bowel or fecal incontinence is still an emerging topic. Despite its relatively new appearance to the field, previous reports indicate that the implementation of rechargeable batteries and MRI-friendly technologies in SNM systems could provide a wide range of benefits to patients with fecal incontinence. This mini review is based on recently conducted experimental studies and will assess the benefits and limitations that new technologies in sacral neuromodulation impose in treating fecal incontinence.

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Section: Axonicsⓡ Devicementioning

confidence: 89%

Use of New Rechargeable Battery and MRI-Friendly Technologies in Sacral Neuromodulation Systems to Treat Fecal Incontinence

J¹,

Csuka²,

Ghoniem³

2020

JJGH

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“…This response was sustained at 6 months. 157,158 The best predictor of success with SNM is a successful trial of test stimulation. Meanwhile, clinical factors such as the presence of a sphincter defect or pudendal neuropathy or a history of a previous sphincter repair do not accurately predict outcomes of SNM.…”

Section: Repeat Anal Sphincter Reconstruction After a Failed Overlapp...mentioning

confidence: 99%

“…156 Rechargeable devices and devices with up to 15 years of battery life are now available and may theoretically decrease the frequency of revisions required because of battery life issues, but clinical studies will need to determine whether this leads to fewer device revisions in the future. 157,158 One small prospective study of 15 patients treated with the rechargeable device implanted in a single stage indicated 50% or more improvement in FI in 13 patients (87%) at 4 weeks. This response was sustained at 6 months.…”

Section: Surgical Managementmentioning

confidence: 99%

The American Society of Colon and Rectal Surgeons’ Clinical Practice Guidelines for the Management of Fecal Incontinence

Bordeianou

Thorsen

Keller

et al. 2023

Diseases of the Colon &Amp; Rectum

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“…This "two-plaque" system may be applied to reinforce any other gut sphincter that has lost its tone and function, for example, the LES, with the aim of preventing gastroesophageal reflux, as it has already been devised and experimented in ex vivo [37] and in vivo [38] animals.…”

Section: Advantages Of the "Two-plaque" Systemmentioning

confidence: 99%

Magnetic sphincter for anal incontinence: an update

Bortolotti¹

2022

Mini-invasive Surg

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The idea of using magnets to control the esophago-gastro-intestinal flow of contents dates back almost 20 years, from the first bench experiment in 2003, published in 2006, while the first clinical application at the anal level to prevent fecal incontinence took place in 2010 by means of a device called FENIX magnetic anal sphincter augmentation (MAS). The clinical experiences with MAS ranged from satisfactory success to partial failure depending on the various studies. The nonrandomized comparisons of MAS with sacral nerve stimulation (SNS) and artificial bowel sphincter (ABS) showed a similar effectiveness in fecal continence and quality of life, whereas the adverse events were more frequent and severe with MAS compared to SNS. ABS either failed to work or required an explantation for infection in 40% of patients, whereas MAS showed these adverse events in only 20% of cases. The comparison of MAS with anal slings and bulking infiltrations provided similar continence results, although with a shorter duration, whereas MAS showed more adverse events. Recently MAS has been withdrawn from the market, creating major inconveniences for surgeons and patients. Nevertheless, this can represent an opportunity for a system that reinforces the anal sphincter with “two magnetic plaques” to be finally implemented for use in patients after completing animal experimentation. This system offers various advantages compared with MAS: it has simpler operational activity, easier surgical implanting procedure, the possibility of “tailored” sphincter augmentation, and should turn out to cost less.

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Treatment of Fecal Incontinence With a Rechargeable Sacral Neuromodulation System: Efficacy, Clinical Outcome, and Ease of Use—Six-Month Follow-Up

Cited by 11 publications

References 13 publications

Use of New Rechargeable Battery and MRI-Friendly Technologies in Sacral Neuromodulation Systems to Treat Fecal Incontinence

Use of New Rechargeable Battery and MRI-Friendly Technologies in Sacral Neuromodulation Systems to Treat Fecal Incontinence

The American Society of Colon and Rectal Surgeons’ Clinical Practice Guidelines for the Management of Fecal Incontinence

Magnetic sphincter for anal incontinence: an update

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