Treatment of hemangiomas of the face with magnesium seeds

Abstract

Various conservative and surgical procedures are available for the management of aggressive hemangiomas in infancy and childhood. One of them is magnesium seeding, a treatment modality developed more than 90 years ago but neglected for a long time. The technique consists of implanting 0.5- to 1-mm-thick wires of 99.8% pure magnesium into the tumor mass. During repeated courses oxidation of the metal results in fibrosis and cicatricial transformation of the tumor. Indications, technique and results are discussed.

Challenges and Pitfalls of Research Designs Involving Magnesium-Based Biomaterials: An Overview

“…In bone surgery, magnesium screws, plates, and sheets were employed to resurface ankylotic joints, resulting in the successful restoration of joint motion and the fixation of fractures [ 277 , 278 ]. In general surgery, magnesium devices, such as arrows and wires, were used to halt bleeding in parenchymatous organs and the treatment of hemangioma cavernous (venous malformation) [ 279 , 280 ].…”

Hämangiome im Säuglings‐ und Kindesalter

“…Für ausgedehnte Hämangiome, insbesondere in peri-und intraorbitaler Lokalisation, wurde auch die Spickungstherapie mit oxidierenden Metallen wie Kupfer oder Magnesium mit gutem Erfolg beschrieben. Auch hierfür ist ein interdisziplinärer Ansatz in spezialisierten Zentren erforderlich [21,31,33]. Für umschriebene Hämangiome wurde alternativ oder in Kombination die intraläsionale Injektion von Glukokortikosteroid-Kristallsuspension beschrieben.…”

Hemangiomas of infancy and childhood

“…Good results in extensive hemangiomas, especially those in a perior intraorbital location, have been reported for seeding with oxidizing metal needles such as copper or magnesium. Here, too, an interdisciplinary approach in specialized centers is essential [21, 31, 33].…”