Treatment of lupus erythematosus of the eyelids with pulsed dye laser

Brás, Susana; Gonzalez, Borja; Segurado‐Miravalles, Gonzalo; Boixeda, P.

doi:10.1007/s10103-016-2131-4

Cited by 6 publications

(2 citation statements)

References 24 publications

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“…A randomized, double-blind, controlled clinical trial including 48 DLE lesions from 9 patients demonstrated that an addition of 595 nm PDL therapy on the basis of conventional treatment improved erythema, texture, and overall skin appearance of DLE. [64] A few cases series have also shown favorable efficacy and safety of PDL treatment in patients with CLE [65][66][67][68][69][70][71][72][73][74][75]. score ≥4) conducted by Yokogawa and colleagues evaluated the efficacy of hydroxychloroquine (HCQ) for treating CLE lesions [76].…”

Section: Recommendationmentioning

confidence: 99%

Guideline for the diagnosis, treatment and long-term management of cutaneous lupus erythematosus

Long

Chow

et al. 2021

Journal of Autoimmunity

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Section: Recommendationmentioning

confidence: 99%

Guideline for the diagnosis, treatment and long-term management of cutaneous lupus erythematosus

Long

Chow

et al. 2021

Journal of Autoimmunity

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“…However, laser treatments in general are still considered dangerous in treating patients with underlying immunologic deficiency or autoimmune connective tissue disease as wound healing in these patients may be impaired 9 10 . Nevertheless, there is not enough scientific evidence neither to confirm nor reverse this common belief in the case of discoid lupus 11 12 13 . It remains to be shown that treatments with infrared laser systems (in this case 10,600 nm) are safe and do not trigger flare-ups of the disease.…”

Section: Introductionmentioning

confidence: 98%

Fractional Photothermolysis for Treatment of a Residual Discoid Lupus Erythematosus Lesion: A Case Report

et al. 2022

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Cutaneous discoid lupus erythematosus (CDLE) is a chronic inflammatory skin disease often resulting in permanent scarring of the affected area. Fractional photothermolysis (FP) is a well-known inducer of tissue regeneration by wounding the skin in a fractional pattern, hence inducing a well defined, wound healing response. It has been used clinically to treat atrophic as well as hypertrophic scars and also fibrotic diseases like morphea since more than a decade. We report a case of a young female patient treated with three sessions of ablative FP for stable atrophic scars due to CDLE affection of the upper left and right cheeks. After the last treatment, no side effects were observed. At the 13-month follow-up visit, the treated atrophic scars showed satisfying improvement for the patient. Skin texture, relief, color, and overall cosmetic appearance were all rated as improved by three independent dermatologists. No signs of unwanted side effects were observed at any time point. This case report should be followed up with a larger case series or ideally a prospective randomized clinical trial to better establish FP as a safe and effective tool to treat reminiscent scars after CDLE.

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