Treatment of Mycobacterium marinum Infections With Minocycline

Lockshin, Norman A.

doi:10.1001/archderm.1977.01640070121036

Cited by 8 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Erythromycin was slightly less inhibitory than the tetracyclines and TMP-S. Although tetracyclines were clinically effective (5,9,(12)(13)(14), two studies noted in vitro resistance of M. marinum to tetracycline at 100 jig/ml (12) and 25 to 50,ug/ml (9). Because these concentrations greatly exceeded the usual achievable blood levels (3 to 6 ,ug/ml), the therapeutic effect was considered by one author to be on a basis other than antibacterial activity (16).…”

Section: Resultsmentioning

confidence: 99%

In vitro susceptibility of Mycobacterium marinum to eight antimicrobial agents

Sanders¹,

Wolinsky²

1980

Antimicrob Agents Chemother

View full text Add to dashboard Cite

The in vitro susceptibilities of 16 Mycobacterium marinum strains to eight antimicrobial agents were determined by the agar dilution technique. The most active drugs were amikacin and kanamycin. Tetracycline, doxycycline, and minocycline were inhibitory, predominantly at concentrations slightly below the expected blood and tissue levels. Trimethoprim-sulfamethoxazole and erythromycin demonstrated activity only at concentrations greater than those usually attained in serum and tissues. Gentamicin was relatively inactive.

show abstract

Section: Resultsmentioning

confidence: 99%

In vitro susceptibility of Mycobacterium marinum to eight antimicrobial agents

Sanders¹,

Wolinsky²

1980

Antimicrob Agents Chemother

View full text Add to dashboard Cite

show abstract

“…1), first synthesized in 1967, is a semi-synthetic second-generation tetracycline derivative (Qiu et al 2019). Many pathogenic mycoplasmas, chlamydias, spirochetes, rickettsias, and enterococci such as Borrelia recurrentis, Mycobacterium marinum, Mycoplasma pneumoniae, and Vibrio vulnificus are susceptible to MC (Chuang et al 1997, Lockshin 1977, Muellegger et al 1995, Rose and Vanderloo 2011 .…”

Section: Introductionmentioning

confidence: 99%

Selective and rapid detection of minocycline in milk using a novel fluorescence conjugated polymer probe

Gong,

Zhang,

Wang

et al. 2024

Preprint

View full text Add to dashboard Cite

Minocycline is a broad-spectrum antibiotic widely used in clinical and veterinary medicine and its adverse effects are as prominent as its potent efficacy. To avoid its abuse and accumulation, it is very important to detect minocycline in medical science, food industry, and aquaculture industry. Here, a conjugated polymer probe for minocycline is prepared and its optical properties and fluorescence response to minocycline is studied. The quenching efficiency is linear relevant with the amount of minocycline at the concentration range of 0–12 µM in PBS and 0–28 µM in ethanol with the limit of detection of 0.0151 µM. Moreover, the standard addition recoveries of minocycline in skim milk samples are between 92.22–104.43%, and the relative standard deviation values are less than 3%. These results imply that the probe has a great potential for detecting minocycline in actual samples with simplify, rapidity and sensitivity.

show abstract

Aquarium-Borne Mycobacterium marinum Skin Infection

Huminer¹,

Pitlik²,

Block³

et al. 1986

Arch Dermatol

114

View full text Add to dashboard Cite

A 33-year-old fish fancier developed a protracted skin infection that ultimately was found to be caused by Mycobacterium marinum. The organism was isolated from the lesion as well as from infected fish taken from his home aquarium. The lesion resolved after a six-week course of oral sulfamethoxazole and trimethoprim. Forty-four additional cases of culture-proved M marinum skin infections acquired from aquariums and reported in the English-language literature are reviewed. Almost universally, the lesions remained circumscribed and were either single nodular (14 patients) or multiple sporotrichoid (31 patients). Diagnosis was supported by acid-fast smears (15 patients) and isolation of the organism from skin lesions (43 patients) or from fish (two cases). In vitro studies, as well as clinical outcomes, suggest sulfamethoxazole-trimethoprim or ethambutol hydrochloride plus rifampin to be the drugs of choice.

show abstract

Treatment of Mycobacterium marinum Infections With Minocycline

Cited by 8 publications

References 4 publications

In vitro susceptibility of Mycobacterium marinum to eight antimicrobial agents

In vitro susceptibility of Mycobacterium marinum to eight antimicrobial agents

Selective and rapid detection of minocycline in milk using a novel fluorescence conjugated polymer probe

Aquarium-Borne Mycobacterium marinum Skin Infection

Contact Info

Product

Resources

About