Treatment of Oligospermia with the Amino Acid Arginine

Schachter, A; Goldman, Jack A.; Zukerman, Zvi

doi:10.1016/s0022-5347(17)60199-x

Cited by 49 publications

(14 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The interruption of tubal patency and ovulation disorders, such as amenorrhoea, anovulatory menstruation, and sporadic anovulatory disorders are causes of female infertility. Spermatogenesis is affected by numerous nutrients and enzymes, such as vitamin (C, E, B12) (Sandler and Faragher, 1984;Rolf et al, 1999), mineral (zinc, copper, selenium, calcium) (Scott et al, 1998), amino acid (Schacter et al, 1973), coenzyme Q10 (Lewin and Lavon, 1997).…”

Section: Discussionmentioning

confidence: 99%

The spermatogenic and ovogenic effects of chronically administered Shilajit to rats

Park

Kim²,

Han

2006

Journal of Ethnopharmacology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

The spermatogenic and ovogenic effects of chronically administered Shilajit to rats

Park

Kim²,

Han

2006

Journal of Ethnopharmacology

View full text Add to dashboard Cite

“…Spermatogenesis is affected by a wide variety of nutrients and enzymes, such as vitamins (C, E, B12) (Sandler and Faragher, 1984; Rolf et al ., 1999), minerals (zinc, copper, selenium, and calcium) (Scott et al ., 1998), amino acids (Schachter et al ., 1973) and Coenzyme Q10 (Lewin and Lavon, 1997). However, no reports have been issued on the spermatogenic activity of polyphenols, like chlorogenic acid, caffeic acid and ferulic acid.…”

Section: Discussionmentioning

confidence: 99%

The Spermatogenic Effect of Yacon Extract and Its Constituents and Their Inhibition Effect of Testosterone Metabolism

Park¹,

Han²

2013

Biomolecules and Therapeutics

View full text Add to dashboard Cite

We screened the pharmacological effects of a 50% ethanol extract of Yacon tubers and leaves on spermatogenesis in rats. As a result, we found that Yacon tuber extracts increased sperm number and serum testosterone level in rats. It has been reported that the crude extract of Yacon tubers and leaves contain phenolic acids, such as, chlorogenic acid, ferulic acid and caffeic acid by HPLC/MS analysis. We were interested in the contributions made by phenolic acid, particularly chlorogenic acid of Yacon tuber extract to the spermatogenic activity. After administering Yacon tuber extract or chlorogenic acid to rats for 5 weeks, numbers of sperm in epididymis were increased by 34% and 20%, respectively. We also administered ferulic acid, which has been reported to be a metabolite of chlorogenic acid and a constituent of Yacon tuber extract to investigate its spermatogenic activity in rats. Yacon tuber extract and ferulic acid increased sperm numbers by 43% and 37%, respectively. And, Yacon tuber extract, and chlorogenic acid showed significantly inhibition effect of testoeterone degradation in rat liver homogenate. We considered that the spermatogenic effect of Yacon tuber extract might be related to phenolic compounds and their inhibitory effect of testosterone degradation. Yacon showed the possibility as ameliorable agents of infertility by sperm deficiency and late onset hypogonadism syndrome with low level of testosterone.

show abstract

“…Some studies have reported that daily supplementation of arginine improves semen concentration and sperm motility (Holt & Albanese, 1944;Tanimura, 1967;Schachter et al, 1973;De-Aloysio et al, 1982;Scibona et al, 1994), while other authors did not succeed on showing any improvement in sperm characteristics or pregnancy rate (Mroueh, 1970;Pryor et al, 1978). There are also studies that have shown that arginine in excessive concentrations results in decrease on sperm function (Srivastava & Agarwal, 2010).…”

Section: Argininementioning

confidence: 99%

Nutraceutical in male reproduction

Freitas¹,

Oliveira

2018

Braz. J. Vet. Med.

View full text Add to dashboard Cite

In order to obtain a successful outcome in artificial insemination programs, a few precautions must be taken with regard to male breeders. It is established that environmental factors can change the hormonal secretion, the cell differentiation that occurs in the testicles, as well as sperm maturation and transport in the epididymis. In view of adverse nutritional factors, reproductive organs can present degeneration and disorders in different degrees and intensities, affecting the animal fertility. The term nutraceutical describes products derived from foods, which may provide additional health benefits, beyond the basic value found in diets. Among the main nutraceuticals used in male reproduction, there are omega-3, arginine, B-complex vitamins, L-carnitine, β-carotene and antioxidants. The aim of this paper is to present the main substances used as nutraceuticals, in order to improve semen quality, obtaining most favorable outcomes of stallions in the use of natural breeding or artificial insemination.Keywords: artificial insemination, fertility, nutrition, semen, spermatogenesis.resumo Para um sucesso em programas de inseminação artificial, algumas precauções devem ser tomadas em relação aos reprodutores machos. Sabe-se que fatores ambientais podem alterar a secreção hormonal, a diferenciação celular que ocorre nos testículos, assim como o transporte e a maturação espermática no epidídimo. Um déficit nutricional pode levar a degeneração e distúrbios dos órgãos reprodutivos em diferentes graus e intensidade, afetando a fertilidade. O termo nutracêutico descreve produtos derivados dos alimentos, que podem fornecer benefícios adicionais a saúde, além dos valores básicos encontrados na dieta. Entre os vários nutracêuticos utilizados na reprodução, temos o ômega-3, arginina, vitaminas do complexo B, L-carnitina, β-caroteno e antioxidantes. Objetivou-se com essa revisão apresentar as principais substâncias utilizadas como nutracêuticos, com a finalidade de melhorar a qualidade seminal, obtendo resultados favoráveis dos garanhões com a monta natural ou a inseminação artificial.Palavras-chave: inseminação artificial, fertilidade, nutrição, sêmen, espermatogênese.

show abstract

Treatment of Oligospermia with the Amino Acid Arginine

Cited by 49 publications

References 1 publication

The spermatogenic and ovogenic effects of chronically administered Shilajit to rats

The spermatogenic and ovogenic effects of chronically administered Shilajit to rats

The Spermatogenic Effect of Yacon Extract and Its Constituents and Their Inhibition Effect of Testosterone Metabolism

Nutraceutical in male reproduction

Contact Info

Product

Resources

About