Treatment of Orbital Pseudotumors and Lymphoma

The Efficacy of Radiotherapy in the Treatment of Orbital Pseudotumor

“…Overall, 9 patients (75%) receiving one course of therapy showed clinical improvement. These findings are consistent with the favorable response findings reported previously (5,7,(10)(11)(12)(14)(15)(16). Encouragingly, none of our patients have developed systemic disease such as lymphoma as has been reported in other series (7,11,13,15,16).…”

“…Encouragingly, none of our patients have developed systemic disease such as lymphoma as has been reported in other series (7,11,13,15,16). However, it should be noted that none of the patients in our series had an initial or follow-up diagnosis of lymphoma in contrast to other series (14,15).…”

“…Orbital pseudotumor has historically been treated using a combination of corticosteroids, radiation therapy, and surgery. The use of low-dose orbital irradiation in the treatment of orbital pseudotumor has been successful in the past (5,7,(10)(11)(12)(13)(14)(15)(16).…”

A Clinico-Pathological Analysis of Seventeen Cases of Non-Hodgkin'S Lymphoma Involving the Orbit

“…The newer technique of studying the immunoglobulin gene rearrangement may be helpful in documenting the clonal nature of these lesions and to confirm their B-lineage (13). Similar to other reports, our 4 patients (Nos 1-4) with clinically localized small lymphocytic lymphoma responded favourably to local radiotherapy (2)(3)(4)(5).…”

Sinonasal inflammatory myofibroblastic pseudotumor (plasma cell granuloma)

“…Unlike orbital localizations, sinonasal IMPT never transform into lymphoma or develop into systemic lymphoma. [18] Despite initial aggressive clinical and radiologic presentations, sinonasal IMPT has a good prognosis. Surgery, corticosteroids, radiotherapy and chemotherapy have been used in the treatment of these tumors.…”