Treatment of Refractory Atopic Dermatitis Using ‘Wet-Wrap’ Dressings and Diluted Corticosteroids: Results of Standardized Treatment in both Children and Adults

Devillers, A. C. A.; Spek, Flora B. de Waard‐van der; Mulder, Paul; Oranje, A.P.

doi:10.1159/000051810

Cited by 47 publications

(63 citation statements)

References 14 publications

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“…At the same time the dressings prevent scratching, due to their textile barrier effect on the inflamed skin [11]. Patients with AD feel comfortable with wet-wraps on their inflamed skin due to these effects [14], whereas this treatment does not lead to a bacterial superinfection [7]. …”

Section: Discussionmentioning

confidence: 99%

Efficacy of Crisis Intervention Treatment with Topical Corticosteroid Prednicarbat with and without Partial Wet-Wrap Dressing in Atopic Dermatitis

et al. 2006

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Background: The wet-wrap treatment has been reported to be beneficial in acute episodes of atopic dermatitis (AD) skin lesions. Objective: The efficacy of topical corticosteroid prednicarbat with and without additional wet-wrap dressing was investigated in a prospective, randomized and controlled study. Methods: In the left-right comparison study, 24 adults and children with an acute episode of AD were included. One arm or leg was randomly treated with the topical corticosteroid prednicarbat plus wet-wrap dressing; only prednicarbat was applied on the leg or arm of the other side. Results: After 48–72 h of treatment, in both groups an improvement of the local SCORAD was observed. In comparison to the side of the body treated with corticosteroid alone, the decrease of the local SCORAD in the corticosteroid plus wet-wrap dressing group was significantly better. The severity of AD improved in the wet-wrap group at an average of 4.4 points, in the corticosteroid group 3.0 (p < 0.011). Conclusions: Wet-wrap therapy with a topical corticosteroid is an effective treatment option in patients with exacerbated AD. The treatment is helpful in improving skin conditions, shortening the time of corticosteroid application.

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Section: Discussionmentioning

confidence: 99%

Efficacy of Crisis Intervention Treatment with Topical Corticosteroid Prednicarbat with and without Partial Wet-Wrap Dressing in Atopic Dermatitis

et al. 2006

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“…Ayrıca fiziksel bariyer olması nedeniyle kaşıntı-kaşıma siklusunun kırılmasına yardımcı olur. Bu tedavi yönteminin etkinliği yapılan çalışmalarla desteklenmiştir [94][95][96] . En fazla 2 hafta uygulanmalıdır 88,97 .…”

Section: Islak Sargı Uygulamasıunclassified

The Turkish guideline for the diagnosis and management of atopic dermatitis-2018

Ertam¹,

Küçük²,

Alper³

et al. 2018

TURKDERM

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“…However, fasting cortisol levels should be monitored. Safety of this therapy in atopic dermatitis has also been reported [12, 13]. Nonetheless, the clinical and cosmetic improvement achieved may fall short of patient’s expectation and all patients should be made aware of this aspect of the treatment.…”

Section: Introductionmentioning

confidence: 97%

Efficacy of 25% Diluted Fluticasone Propionate 0.05% Cream as Wet-Wrap Treatment in Cutaneous Mastocytosis

Heide

Spek²,

Hollander³

et al. 2007

Dermatology

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Background: Mastocytosis is a disorder that can be subdivided into two forms: cutaneous and systemic. Patients with cutaneous mastocytosis only may suffer from cosmetic problems. Topical steroid application has been shown to be effective in cases of limited skin lesions. Methods: A case-controlled pilot study was conducted during a 6-weeks treatment using diluted 25% fluticasone propionate 0.05% cream under wet-wrap occlusion in 5 adults and 6 children. Improvement was measured up to the 24th week after treatment using the SCORMA Index. Results: The results of this pilot study showed a partial but clear cosmetic improvement in 9 of the 11 patients. The mean SCORMA Index decreased after treatment from 38 to 26. Conclusion: 25% dilution of fluticasone propionate 0.05% cream under wet-wrap occlusion is an alternative treatment modality for alleviating the symptoms of cutaneous mastocytosis, but the improvement may be moderate and fall short of the patient’s expectations.

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Treatment of Refractory Atopic Dermatitis Using ‘Wet-Wrap’ Dressings and Diluted Corticosteroids: Results of Standardized Treatment in both Children and Adults

Cited by 47 publications

References 14 publications

Efficacy of Crisis Intervention Treatment with Topical Corticosteroid Prednicarbat with and without Partial Wet-Wrap Dressing in Atopic Dermatitis

Efficacy of Crisis Intervention Treatment with Topical Corticosteroid Prednicarbat with and without Partial Wet-Wrap Dressing in Atopic Dermatitis

The Turkish guideline for the diagnosis and management of atopic dermatitis-2018

Efficacy of 25% Diluted Fluticasone Propionate 0.05% Cream as Wet-Wrap Treatment in Cutaneous Mastocytosis

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