Treatment of Retinal Separation in HIV-infected Patients with Cytomegalovirus Retinitis

Онищенко, А. Л.; Колбаско, А. В.; Татарникова, Г. Н.; Чернышева, А. Д.

doi:10.18008/1816-5095-2017-1-84-87

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…Plasmapheresis is used in combination with blood cells ozonation [104]. Plasmapheresis or plasma exchange with replacement of the autologous cryosorbed plasma up to 50% of the circulating plasma volume contribute to a faster resolution of the inflammatory process, transition to remission state, disappearance of adhesions even without local proteolytic treatment [105]. Such treatment is also indicated to prevent relapses [106].…”

Section: Atypical Optic Neuritismentioning

confidence: 99%

Plasmapheresis in Ophthalmology

Voinov

Karchevscy

2019

CTOY

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Loss of sight is one of the most severe disabling factors in human. The total number of such people is known to account for millions worldwide. In North America alone more than 1 million are completely blind and about 14 million have some degree of sight loss. There are many different diseases that lead to sight loss such as diabetic retinopathy, senile macular degeneration, various types of autoimmune retinopathy, optic nerves damage and many others. As a rule, they cannot be corrected with glasses, and not always amenable to drug therapy. Often the cause of these diseases is accumulation of various autoantibodies and other metabolites, the molecules large size of which does not allow them to be excreted by the kidneys and the fact of their accumulation indicates impossibility of their removal with help of drug therapy. It makes us resort to such method of their direct removal from the body as plasmapheresis and the aim of this study is to justify its use in ophthalmology.

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Section: Atypical Optic Neuritismentioning

confidence: 99%

Plasmapheresis in Ophthalmology

Voinov

Karchevscy

2019

CTOY

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Visual functions in patients with cytomegalovirus uveitis and HIV infection

Sizova

Хокканен²,

Zumbulidze³

et al. 2022

Ophthalmology Reports

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BACKGROUND: Cytomegalovirus damage to the eye is the leading cause of loss of visual functions associated with HIV. Effective treatment of HIV-infected patients has changed the understanding of the clinical picture of cytomegalovirus uveitis (CMV-uveitis). AIM: The aim of the work is to determine the prevalence, the structure of clinical forms and to evaluate visual functions in HIV-infected patients with CMV-uveitis. MATERIALS AND METHODS: The study group consisted of 66 HIV-infected patients with CMV-uveitis (97 eyes), of which there were 27 men (40.9%), 39 women (59.1%). The average age was 39.6 3.91 years. All patients had stage 4B of HIV infection according to V.V. Pokrovskys classification (2006). During the work, visometry, perimetry, biomicroscopy, ophthalmoscopy were used. RESULTS: The main form of the disease is chorioretinitis, diffuse and generalized forms of the disease are diagnosed in 68.0% of cases. In predicting visual acuity, the leading regression criterion was the clinical form of the disease. CONCLUSIONS: Diffuse and generalized forms of the disease prevailed in clinical practice. Localization of the chorioretinal process of a predominantly diffuse nature predetermined visual acuity, which in more than a third of cases met the criteria for blindness according to the WHO classification (1977).

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Cytomegalovirus uveitis in HIV-infected patients: the main clinical forms

Sizova,

Khokkanen,

Boiko

2023

Rossijskij oftalʹmologičeskij žurnal

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Effective treatment of HIV-infected patients has changed the previous view of the clinical picture of cytomegalovirus uveitis (CMV uveitis).Purpose: to determine the prevalence and structure of clinical forms of CMV uveitis in HIV-infected patients.Material and methods. 66 patients (97 eyes), aged 39.6 ± 3.91, were diagnosed with stage 4c HIV infection. In 35 patients (53%), the duration of infection exceeded 5 years, in 13 patients (19.7%), it exceeded 10 years, and another 13 patients (19.7%) had the condition for over 15 years. The ophthalmological follow-up of patients diagnosed with CMV uveitis ranged from 6 months to 13 years (the median of 45.5 months).Results. By the time CMV uveitis was detected, the median CD4 cell count was 34 cells/μL (the norm being 570–1100 cells/μL). The content of whole blood CMV DNA was 2.43 lg copies/105 cells. The main form of the disease was chorioretinitis, diffuse and generalized forms of the disease were diagnosed in 68.0% of cases. In predicting visual acuity, the leading regression criterion was the clinical form of the disease.Conclusion. Diffuse and generalized forms of the disease prevailed in clinical practice. The prevalence of chorioretinal lesion determined visual acuity, which in 39.2% of the eyes met the criteria for blindness according to the WHO classification (1977)

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Treatment of Retinal Separation in HIV-infected Patients with Cytomegalovirus Retinitis

Cited by 3 publications

References 4 publications

Plasmapheresis in Ophthalmology

Plasmapheresis in Ophthalmology

Visual functions in patients with cytomegalovirus uveitis and HIV infection

Cytomegalovirus uveitis in HIV-infected patients: the main clinical forms

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