Лечение отслойки сетчатки у ВИЧ-инфицированных больных с цитомегаловирусным ретинитом abstraCtHIV infection -is a socially significant problem for many countries, as the infected die in an average of 10-11 years due to the immunodeficiency virus. Up to 20% of patients with AIDS lose their sight because of cytomegalovirus retinitis (CMV retinitis), which occurs in 70% of HIV-infected people. In some patients with HIV infection blindness occurs because of acute retinal necrosis of CMV etiology. The algorithm of CMV retinitis treatment in HIV-infected patients is described in modern manuals (ganciclovir, valganciclovir, foscarnet and others on the background of antiretroviral therapy), but the tactics of treatment of retinal separation in these patients is not clearly defined. It may be "wait and see", providing conservative treatment with antiviral drugs, and the active tacticsvitreoretinal surgery. In this article the authors present their personal clinical observations of three HIV-infected patients with CMV retinitis at the age of 8 to 36 years with a detailed analysis of the clinical data and the results of the laboratory tests. In particular, ophthalmology in russia. 2017;14(1):84-87