Treatment of severe mitral regurgitation caused by lesions in both leaflets using multiple mitral valve plasty techniques in a small dog

Yokoyama, Seiji; Kanemoto, Isamu; Mihara, Kippei; Andô, Tsuyoshi; Kawase, Koudai; Sahashi, Yasuaki; Iguchi, Kosei

doi:10.4314/ovj.v7i4.7

Cited by 3 publications

(10 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, the cardioplegic solution volume was decreased to half of the usual volume (20 ml/kg) to avoid more hemodilution, although we used the lowest deep HT (ET 20°C) for cardioplegia. Thereafter, we used a hemoconcentrator to prevent excess hemodilution due to additional cardioplegic solution ( Taguchi et al ., 2014 ; Mihara et al ., 2017 ; Yokoyama et al ., 2017 ).…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, although the time proportion of surface-cooling and blood rewarming with sHT and CPB was about 2:1 ( Fig. 2 ) ( Yokoyama et al ., 2017 ), the time proportion of the rates of blood cooling and rewarming was reversed to about 1:2 with the bHT and CPB ( Fig. 3 ) ( Mihara et al ., 2017 ).…”

Section: Introductionmentioning

confidence: 99%

“…This SSVP absolutely differs from a magic stitch to repair a shallow cleft in the leaflet ( Carpentier et al ., 2010 ; Varghese and Adams, 2011 ). The advantage is that there is no reduction in the whole size of the PL, and this method is easily adaptable to severe MR cases involving the whole PL in small dogs ( Yokoyama et al ., 2017 ).…”

Section: Introductionmentioning

confidence: 99%

“…As a result, MR flow mostly disappeared without mitral stenosis. Then, this dog safely underwent two major operations: a splenectomy for a splenic tumor at 9 months post-MVP and a right-lung lobectomy for lung cancer at 3 years and 5 months post-MVP ( Yokoyama et al ., 2017 ).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Open-heart techniques and mitral valve plasty for mitral regurgitation in toy- and small-breed dogs: A review

2021

Self Cite

View full text Add to dashboard Cite

In human medicine, in the past, open-heart techniques for low-bodyweight children and newborn babies with congenital heart disease were more difficult than high-bodyweight adults. In toy- and small-breed dogs with mitral regurgitation (MR), an acquired heart disease, these techniques are more difficult to perform than for congenital heart diseases in young medium-sized or large dogs because of old age and low body weight. Therefore, improved open-heart techniques and mitral valve surgery for severe MR in older toy- and small-breed dogs are essential. Through our surface-cooling hypothermia (sHT) studies, we designed a new, improved open-heart method, namely, “the low-flow cardiopulmonary bypass (CPB) combined with deep sHT in toy- and small-breed dogs (Japan method)”; sHT was later replaced by blood-cooling hypothermia (bHT). At the same time, we devised a new, improved mitral valve plasty (MVP) applicable to severe MR, instead of mitral valve replacement, in toy- and small-breed dogs. This MVP technique was combined with artificial chordal reconstruction, semi-circular suture annuloplasty (AP), and direct scallop-suture valvuloplasty. These MVP techniques are simple, durable, and lead to good long-term quality of life in toy- and small-breed dogs. This review highlights the benefits of our improved CPB and MVP techniques (Japan method) for severe MR in toy-and small-breed dogs, which have led to a high success rate for MVP in severe clinical MR cases in Japan. It may further contribute to the development of more robust techniques for MR in toy- and small-breed dogs. This also represents the first comprehensive review of the history of open-heart surgery, CPB techniques, and MVP methods for MR in toy- and small-breed dogs.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Open-heart techniques and mitral valve plasty for mitral regurgitation in toy- and small-breed dogs: A review

2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…, the procedures mostly used in persons are mitral valve repair, valve replacement with a mechanical valve or bioprosthetic valve 33,35,45 . There are very few comparative studies of veterinary patients that have undergone valve surgery, so there is not a clear criteria for which techniques have the best outcome 45,46,47 . Recent reports reveal that the surgical option of mitral valve repair has a better outcome in dogs, using the mitral chordal replacement, with mitral annuloplasty 33,45,46 , valvuloplasty 47 or resection of the prolapsed segment 8 .…”

mentioning

confidence: 99%

Insights on the canine mitral valve in the course of myxomatous mitral valve disease

P¹,

Olivera-Angel

Vargas‐Pinto³

2019

Ces. Med. Vet. Zootec.

View full text Add to dashboard Cite

Myxomatous mitral valve disease (MMVD) is the most common heart alteration in dogs. A vast extent of research has been focused on echocardiographic tissue Doppler and strain indices and the medical treatment of this condition, which are beyond the scope of this article. This review intends to include less known information of the mitral valve, acknowledge the American College of Veterinary Internal Medicine (ACVIM) consensus on MMVD and state different surgical approaches and devices, all valuable information for small animal clinicians and cardiologists. Also, during the last decade studies have been oriented towards to understand valve’s mechanical structure and function, genes involved in the etiology and molecular signaling pathways. Advances have been made in understanding the mitral valve, but more assessment and efforts are needed in this specific area.

show abstract

Changes in renin‐angiotensin‐aldosterone system during cardiac remodeling after mitral valvuloplasty in dogs

Cheng

Mandour

Yoshida

et al. 2022

Veterinary Internal Medicne

View full text Add to dashboard Cite

Background Information regarding changes in renin‐angiotensin‐aldosterone system (RAAS) during cardiac remodeling after mitral valvuloplasty (MVP) in dogs remains lacking. Hypothesis/Objectives To assess the longitudinal effects of MVP on circulating RAAS activity. Animals Eight client‐owned dogs receiving MVP for myxomatous mitral valve disease (MMVD). Methods This is a cohort study. Plasma renin activity (PRA), angiotensin II (AT2), aldosterone (PAC), blood urea nitrogen (BUN), and creatinine concentrations, were measured in these dogs before (baseline) and at 3 consecutive monthly follow‐ups (Post‐1M, Post‐2M, Post‐3M). Echocardiography was concomitantly used to assess the process of cardiac recovery after MVP. Results The echocardiography revealed a significant decrease in LVIDDN, LA/Ao, FS, E velocity, E/A, E′ sep, S′ lat, E′ lat, and A′ lat after MVP compared with baseline (P < .05). There was a significant reduction in the PRA (2.45, 3.05, 2.74 vs 8.8 ng/mL/h; P = .002), AT2 (466, 315, 235 vs 1200 pg/mL; P = .009), and PAC (39.88, 47, 54.62 vs 179.5 pg/mL; P = .01), respectively at Post‐1M, Post‐2M, Post‐3M compared to the baseline. Additionally, BUN and creatinine concentrations decreased from Post‐1M. The RAAS variables showed significant, weak to moderate, relationship with selected echocardiographic variables. Conclusions and Clinical Importance Mitral valvuloplasty contributes to decreased RAAS activity in MMVD dogs, which paralleled the process of cardiac reverse remodeling up to Post‐3M. This information facilitates formulating strategies to optimize clinical outcomes for dogs after MVP.

show abstract

Treatment of severe mitral regurgitation caused by lesions in both leaflets using multiple mitral valve plasty techniques in a small dog

Cited by 3 publications

References 12 publications

Open-heart techniques and mitral valve plasty for mitral regurgitation in toy- and small-breed dogs: A review

Open-heart techniques and mitral valve plasty for mitral regurgitation in toy- and small-breed dogs: A review

Insights on the canine mitral valve in the course of myxomatous mitral valve disease

Changes in renin‐angiotensin‐aldosterone system during cardiac remodeling after mitral valvuloplasty in dogs

Contact Info

Product

Resources

About