1987
DOI: 10.1111/j.1524-4725.1987.tb02429.x
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Treatment of Telangiectasia: Comparison of Sclerosing Agents

Abstract: A double-blind, double-paired comparison, placebo-controlled study was undertaken to determine the optimal agent for sclerotherapy of spider telangiectasias of the lower extremities. Sodium tetradecyl sulfate 0.5%, polidocanol 0.25%, heparsal, and normal saline control were evaluated in terms of clinical effectiveness and patient acceptance. Although all of the agents, except for the control, were effective, polidocanol was found to have the fewest adverse reactions and afforded the greatest patient comfort.

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Cited by 57 publications
(32 citation statements)
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“…All sclerosants, excluding placebo, had similar efficacy. The lowest incidence of adverse events and greatest patient comfort was noted with POL . As mentioned above, STS has at least twice the potency of POL .…”
Section: Discussionmentioning
confidence: 78%
“…All sclerosants, excluding placebo, had similar efficacy. The lowest incidence of adverse events and greatest patient comfort was noted with POL . As mentioned above, STS has at least twice the potency of POL .…”
Section: Discussionmentioning
confidence: 78%
“…Estes últimos são mais efetivos para os vasos, porém, são mais agressivos para a pele 11 . A glicose hipertônica constitui-se em um dos esclerosantes mais importantes 12 …”
Section: Discussionunclassified
“…It can be effective in saphenofemoral incompetence, when surgical treatment is contraindicated. Relief of symptoms occurs in up to 85% of patients with varicose and telangiectatic veins [36]. Modern sclerotherapy treatment has been shown to be simple and safe, with low risk of significant side effects and efficacy comparable to surgical procedures in appropriately selected patients.…”
Section: Skin Substitutesmentioning
confidence: 99%