Treatment of thyroid associated ophthalmopathy with periocular injections of triamcinolone

Ebner, Roberto; Devoto, Martín H.; Weil, D.; Bordaberry, Marcela F; Mir, Carme; Martinez, Henry; Bonelli, Laura; Nièpomniszcze, Hugo

doi:10.1136/bjo.2004.046193

Cited by 116 publications

(85 citation statements)

References 33 publications

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“…Corticosteroid injection into the eyelids and orbit has been reported as a successful treatment for numerous periocular disease processes, such as capillary hemangioma, 13 thyroid ophthalmopathy, 14 chalazia, 15 sarcoid, 16 and vernal keratoconjunctivitis. 17 More inconsistent results have been reported with sporadic use of intralesional corticosteroids for the treatment of periocular NXG.…”

Section: Discussionmentioning

confidence: 99%

Local Corticosteroid Treatment of Eyelid and Orbital Xanthogranuloma

Elner¹,

Mintz²,

Demirci³

et al. 2006

Ophthalmic Plastic & Reconstructive Surgery

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Purpose: To demonstrate the efficacy of local corticosteroid therapy for the treatment of eyelid and orbital xanthogranuloma in adults.Methods: We performed a retrospective chart review of six patients receiving local triamcinolone acetonide (40 mg/mL) injections for the treatment of eyelid and orbital xanthogranuloma at the University of Michigan. All patients underwent diagnostic biopsy prior to treatment. The effects of this therapy on symptoms and signs of the disease were assessed.

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Section: Discussionmentioning

confidence: 99%

Local Corticosteroid Treatment of Eyelid and Orbital Xanthogranuloma

Elner¹,

Mintz²,

Demirci³

et al. 2006

Ophthalmic Plastic & Reconstructive Surgery

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“…[5][6][7] They have an anti-inflammatory action by inhibiting prostaglandin and leukotriene production, and by eliciting apoptosis in inflammatory cells such as T-lymphocytes. 8,9 The exact mechanism of action of triamcinolone, concerning reduction of macular oedema, remains uncertain.…”

Section: Discussionmentioning

confidence: 99%

Ocular morbidity associated with intravitreal triamcinolone acetonide

Konstantopoulos¹,

Williams²,

Newsom³

et al. 2006

Eye

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Aim To report on the complications associated with the use of intravitreal triamcinolone acetonide (IVTA) in a tertiary referral hospital setting. Materials and methods A retrospective case series review of all IVTA injections carried out over a period of 30 months. Results One hundred and thirty IVTA injections were performed; nine with limited local follow-up were excluded. Thus, 121 injections (108 patients, 114 eyes) were included in the study. Triamcinolone (4 mg) was used in all cases. Indications were diabetic macular oedema (n ¼ 41 eyes), retinal vein occlusions (n ¼ 27), postoperative cystoid macular oedema (n ¼ 24), exudative age-related macular degeneration (n ¼ 16), and others (n ¼ 6). No intraoperative complications were recorded. Postoperative intraocular pressure (IOP) readings of 22, 28, 35, and 40 mmHg or higher were recorded in 46.5, 29.8, 12.3, and 7.9% of eyes, respectively. IOP elevation was treated with antiglaucoma medication in all but one eye (0.9%) that required trabeculectomy and one (0.9%) that required vitrectomy with cataract extraction for suspected phacoanaphylactic glaucoma. Two eyes (1.8%) developed retinal detachment; both had previously been treated for retinal breaks. One eye (0.9%) developed culture-positive endophthalmitis. Conclusions Significant morbidity is associated with IVTA injection; clinicians should be aware when considering treatment options.

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“…2,6-8, 13 Recently, ophthalmologists reported the use of orbital steroid injections for the treatment of Graves disease. 14,15 Periocular injections of steroids can reduce diplopia rates, decrease extraocular muscle size, 15 and reverse Graves compressive optic neuropathy. 14 Ocular hypertension, posterior subcapsular cataract formation, delayed wound healing, and infection are potential side effects of corticosteroids.…”

Section: Discussionmentioning

confidence: 99%

Steroid-induced ptosis: case studies and histopathologic analysis

Song

Carter

Nerad

et al. 2007

Eye

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Purpose The purpose of this study was to review patients who developed ptosis after subtenon's steroid injection and to study the mechanism of steroid-induced ptosis in an animal model. Methods Part 1. Twenty-two patients with uveitis who had received posterior subtenon's triamcinolone acetonide injections were retrospectively reviewed. Demographics, type of uveitis, type and number of surgeries, pre and postoperative marginal reflex distance (MRD1), and clinical outcomes were evaluated. Part 2. Study of rabbit levator muscle and aponeurosis histopathology after subtenon's triamcinolone injection was performed. Results Part 1. The average age was 44.6 years (range: 14 -85

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Treatment of thyroid associated ophthalmopathy with periocular injections of triamcinolone

Cited by 116 publications

References 33 publications

Local Corticosteroid Treatment of Eyelid and Orbital Xanthogranuloma

Local Corticosteroid Treatment of Eyelid and Orbital Xanthogranuloma

Ocular morbidity associated with intravitreal triamcinolone acetonide

Steroid-induced ptosis: case studies and histopathologic analysis

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