Treatment of tophaceous pseudogout in the temporomandibular joint with resection and alloplastic reconstruction: a single-staged approach

Dang, Rushil R.; Noonan, Vikki; Chigurupati, Radhika; Henry, Andrew

doi:10.1007/s10006-021-01013-2

Cited by 3 publications

(1 citation statement)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CPPD of the TMJ poses diagnostic challenges; a likely justification for its rarity in the literature [19][20][21]. Although the diagnosis of CPPD is based on described criteria [22], highlighted in Table 1, the identification of parallelepipedic, principally cellular deposits of crystals with absent or weak positive birefringence in the synovial fluid or tissue of the affected joint (criterion IIa) may be challenged by the presence of other birefringent crystals such as calcium oxalate, synthetic steroids, and ethylenediaminetetraacetic acid in the joint fluids and tissues [23,24].…”

Section: Introductionmentioning

confidence: 99%

Management of temporomandibular joint diseases: a rare case report of coexisting calcium pyrophosphate crystal deposition and synovial chondromatosis

Murahashi

Ntege

Higa³

et al. 2022

BMC Oral Health

View full text Add to dashboard Cite

Background The coexistence of calcium pyrophosphate dihydrate crystal deposition (CPP) and synovial chondromatosis (SC) in the temporomandibular joint (TMJ) is rarely reported. CPP disease (CPPD) is complex arthritis synonymous with excessive pyrophosphate production and variable aberrations in mineral and organic phase metabolism of the joint cartilage, leading to local inundated CPP and crystal deposition of partially deciphered predispositions. Meanwhile, SC is a rare benign synovial joint proliferative disease of unclear etiology and has a low risk of malignant transformation. However, SC manifests severe joint disability and dysfunction because of connective tissue metaplasia of the synovial membrane, which forms cartilaginous nodules with or without calcifications or ossifications. These nodules often detach and form intra-articular loose bodies and very rarely within extraarticular spaces. Case presentation We report the case of a 61-year-old man to expand the body of literature on these unusual coexisting arthropathies of the TMJ. The patient presented to our hospital in 2020 with complaints of pain in the right TMJ and trismus for over 6 months. Radiographic assessments of the TMJ provided a preoperative provisional diagnosis of SC. However, the histopathology of the open biopsy revealed tumor-like lesions comprising several deposits of rhomboid and rod-shaped crystals that displayed positive birefringence in polarized light, confirming a coexistence of CPPD. A second-stage operation was performed for the complete removal of the loose bodies and chalk-like lesions including synovectomy. No evidence of recurrence was recorded after a follow-up of nearly 1.5 years. Conclusions Isolated CPPD and SC of the TMJ are prevalent in the literature however, monoarticular coexistence of these diseases is rare, due to the lack of consistency in the diagnostic criteria in clinical practice. Moreover, optimal treatment depends on several considerations. This report delineated the molecular etiopathology and underscored the need for continued deciphering of the causal mechanisms of coexisting CPPD and SC of the TMJ. In addition, the importance of confirmatory testing for accurate diagnosis, and appropriate management of these diseases were discussed.

show abstract

Section: Introductionmentioning

confidence: 99%

Management of temporomandibular joint diseases: a rare case report of coexisting calcium pyrophosphate crystal deposition and synovial chondromatosis

Murahashi

Ntege

Higa³

et al. 2022

BMC Oral Health

View full text Add to dashboard Cite

show abstract

Crowned “Mandible” Syndrome: Crystal-induced Arthritis of the Temporomandibular Joint

Mizumoto

2024

The American Journal of Medicine

View full text Add to dashboard Cite

Treatment strategies for calcium pyrophosphate deposition disease

Turlej,

Gaffo

2024

Explor Musculoskeletal Dis

View full text Add to dashboard Cite

Calcium pyrophosphate deposition disease (CPPD) is a cause of inflammatory arthropathy that increases in prevalence with increasing age, presents in acute and chronic forms, and is characterized by the finding of positively birefringent crystals on polarized microscopy of synovial fluid. This review finds that although strides are being made in CPPD diagnosis and classification, CPPD remains a poorly understood, unrecognized, and debilitating disease. As a consequence, treatment options usually lack supportive evidence and there has been little progress in novel drug development for the condition. This article aims to discuss the updated evidence on treatment options for CPPD and identifies promising future areas for improvement.

show abstract

Treatment of tophaceous pseudogout in the temporomandibular joint with resection and alloplastic reconstruction: a single-staged approach

Cited by 3 publications

References 18 publications

Management of temporomandibular joint diseases: a rare case report of coexisting calcium pyrophosphate crystal deposition and synovial chondromatosis

Management of temporomandibular joint diseases: a rare case report of coexisting calcium pyrophosphate crystal deposition and synovial chondromatosis

Crowned “Mandible” Syndrome: Crystal-induced Arthritis of the Temporomandibular Joint

Treatment strategies for calcium pyrophosphate deposition disease

Contact Info

Product

Resources

About