1989
DOI: 10.1159/000181327
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Treatment of Uterine Leiomyomata: Past, Present and Future

Abstract: Hysterectomy for uterine leiomyomata can now be considered a safe procedure, but preoperative LHRH analogue administration greatly facilitates the surgical procedure, allowing myomectomy, when otherwise a hysterectomy may have been necessary. In selected cases, especially near the end of the reproductive period, LHRH analogues may become a valid alternative to hysterectomy.

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Cited by 21 publications
(15 citation statements)
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“…Newer techniques to decrease adhesion formation include micro‐surgery 20 and the use of CO 2 , YAG or Argon lasers. Maheux 2 reports that lasers are unhelpful in laparotomic myomectomy. In contrast, others 21–23 believe that minimal blood loss, fewer adhesions and decreased anatomical disruption can improve long‐term results, especially in infertile patients.…”
Section: Conservative Surgical Managementmentioning
confidence: 99%
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“…Newer techniques to decrease adhesion formation include micro‐surgery 20 and the use of CO 2 , YAG or Argon lasers. Maheux 2 reports that lasers are unhelpful in laparotomic myomectomy. In contrast, others 21–23 believe that minimal blood loss, fewer adhesions and decreased anatomical disruption can improve long‐term results, especially in infertile patients.…”
Section: Conservative Surgical Managementmentioning
confidence: 99%
“…Essentially, two approaches have been tried to maintain the good results obtained through the use of GnRH analogues, without maintaining women in a state of severe hypo‐oestroge‐nism. Friedman 34 and Maheux 2 have treated women with a GnRH analogue until the size of the uterus and that of leiomyo‐mas had properly diminished; at that stage, while continuing treatment with the analogue, they added small quantities of an oestrogen, followed by a progestogen, as in hormonal replacement therapy. In a pilot study, our group has added a progestogen alone.…”
Section: Management Of Women Who Have Completed Their Reproductive Cyclementioning
confidence: 99%
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“…This might be minimized by combined therapy. Preliminary experience of the combination of combined oestrogen‐progestogen hormone‐replacement therapy with goserelin appears to be promising 17,18 ; however, concern remains that the dose of steroids required to be bone sparing may, in some women, lead to fibroid regrowth and/or a return of menstrual symptoms. We have investigated two alternative approaches to medical management.…”
Section: Medical Treatment: Combined Therapymentioning
confidence: 99%