Abstract:Diets high in fat and sugar (HFSD) adversely affect bone mineralization during growth and are implicated in osteoporosis in obese adults. In this study, we assessed fracture risk in mice fed a standard diet and mice fed HFSD. We evaluated fracture risk using three‐point bending tests and comparisons of cross‐sectional geometric properties of the femur. We also investigated the effects of low‐intensity exercise and dietary genistein, an isoflavone, on fracture risk in HFSD‐fed mice. We tested the hypothesis usi… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.